|
INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
Imp Links for Author
Imp Links for Reviewer
Research Area
Subscribe IJSDR
Visitor Counter
Copyright Infringement Claims
Indexing Partner
|
Published Paper Details
|
|
| Paper Title: | Oxidative Spectrophotometric Determination Of Clopidogrel In The Presence Of Aspirin Using Ceric Ammonium Nitrate (CAN) |
| Authors Name: | I LAKSHMI PRASANNA , G.T. Naidu , Nuzhath Fathima , G. Abdul Huq |
| Unique Id: | IJSDR1807055 |
| Published In: | Volume 3 Issue 7, July-2018 |
| Abstract: | A simple, precise, accurate and versatile new spectrophotometric method is proposed for the estimation of micro determination of the drug Clopidogrel in the presence of Asprin using CAN. It is also known as Clopin-A. During the course of study, it is observed that acidic solution of the drug, when treated with CAN forms the oxidation product which is exploited for the development of spectrophotometric method for the determination and analysis of the drug. The oxidation product showed λmax at 300 nm. Applicability of Beer- Lamberts law showed the linearity range for Clopidogrel in the presence of Aspirin is found to be 20 μg/ml to 200 μg/ml. Recovery studies gave satisfactory results indicating that none of common additives and excipients interfere the assay method. The molar absorptivity and the sandell sensitivity of the method are evaluated and the values are found to be to be 2.8162x 104 lit/ mole/cm and 0.0149 μg/ ml/ cm2 respectively. |
| Keywords: | Spectrophotometry, Clopidogrel, Asprin, Oxidation method, CAN, Pharmaceutical Formulations |
| Cite Article: | "Oxidative Spectrophotometric Determination Of Clopidogrel In The Presence Of Aspirin Using Ceric Ammonium Nitrate (CAN)", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.3, Issue 7, page no.328 - 333, July-2018, Available :http://www.ijsdr.org/papers/IJSDR1807055.pdf |
| Downloads: | 000337070 |
| Publication Details: | Published Paper ID: IJSDR1807055 Registration ID:180557 Published In: Volume 3 Issue 7, July-2018 DOI (Digital Object Identifier): Page No: 328 - 333 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijsdr.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
Track Paper
Important Links
Conference Proposal
ISSN
 |
 |
DOI (A digital object identifier)
  Providing A digital object identifier by DOI How to GET DOI and Hard Copy Related |
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
 |
 |
 |
Social Media
Indexing Partner |
|||
| Copyright © 2024 - All Rights Reserved - IJSDR | |||
Facebook Twitter Instagram LinkedIn