INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Evaluation of Antibacterial and Antioxidant Activity of ( Petthan) Fernandoa adenophylla Bark
Authors Name:
Maw Maw Than
, Hla Myoe Min
Unique Id:
IJSDR1808032
Published In:
Volume 3 Issue 8, August-2018
Abstract:
Firstly, (Petthan) Fernandoa adenophylla bark extracts were prepared using normal hexane, ethyl acetate and methanol by percolation method and antibacterial activity of these extracts were screened by agar well diffusion method using six human pathogens; Bacillus cereus, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhi, Shigella boydii and Escherichia coli. The result showed the significant inhibition for ethyl acetate extract and good for methanol extract. Again, antibacterial screening for ethyl acetate extract was performed by immersion bioautography method using two pathogens; Bacillus cereus and Shigella boydii. Hence, the fraction (Rf values range 0.16-0.84) of ethyl acetate extract which has broad spectrum of activity was found. Secondly, antioxidant activity of ethyl acetate and methanol extract were evaluated by DPPH assay method by comparing with that of ascorbic acid. Both extracts have good antioxidant activity. Then, TLC screening for antioxidant activity of ethyl acetate extract was done by spraying 20% solution of molybdophosphoric acid in ethanol. The Rf values given by antioxidant compounds were within the Rf values range having broad spectrum of antibacterial activity. This finding suggested that the compounds having antibacterial and antioxidant activity could be present in ethyl acetate of Petthan bark.
Keywords:
Fernandoa adenophylla, extract, antibacterial, human pathogen, bioautography, broad spectrum, antioxidant
Cite Article:
"Evaluation of Antibacterial and Antioxidant Activity of ( Petthan) Fernandoa adenophylla Bark", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.3, Issue 8, page no.200 - 203, August-2018, Available :http://www.ijsdr.org/papers/IJSDR1808032.pdf
Downloads:
000336256
Publication Details:
Published Paper ID: IJSDR1808032
Registration ID:180599
Published In: Volume 3 Issue 8, August-2018
DOI (Digital Object Identifier):
Page No: 200 - 203
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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