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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Microarray Technology: Transcending Towards New Era of Gene Expression and Its Potential Applications |
| Authors Name: | Virendra Kumar Vishwakarma , Tarun Gupta , Kesana Veekshitha |
| Unique Id: | IJSDR1901033 |
| Published In: | Volume 4 Issue 1, January-2019 |
| Abstract: | Examination of the transcriptome utilizing DNA microarrays has turned into a standard methodology for examination of the atomic premise of human malady in both clinical and trial settings. Microarray innovation has gained solid ground over the previous decade, and there have additionally been critical changes in application territories, from nucleic acids to proteomics and from research to clinical applications. This audit gives a far reaching review of microarrays in diagnostics and biomarker, covering DNA, peptide, protein exhibits. DNA microarrays, or quality chips, permit reviews of quality articulation, (i.e., mRNA articulation) in a very parallel and complete way. The example of quality articulation created, known as the articulation profile, portrays the subset of quality transcripts communicated in a cell or tissue. At its most crucial dimension, the articulation profile can address subjectively which qualities are communicated in ailment states. Microarrays can be utilized to describe the elements of novel qualities, distinguish qualities in a biologic pathway, investigate hereditary variety, and recognize remedial medication targets. Late advances in microarray-based innovations take into account vast scale quality articulation examination in a solitary trial, which have been connected to far reaching tests, mutational investigation, medicate revelation, formative science, and sub-atomic investigation of different infections. |
| Keywords: | DNA microarray; gene expression; biomarker; Gene regulation |
| Cite Article: | "Microarray Technology: Transcending Towards New Era of Gene Expression and Its Potential Applications", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.4, Issue 1, page no.186 - 194, January-2019, Available :http://www.ijsdr.org/papers/IJSDR1901033.pdf |
| Downloads: | 000337211 |
| Publication Details: | Published Paper ID: IJSDR1901033 Registration ID:190027 Published In: Volume 4 Issue 1, January-2019 DOI (Digital Object Identifier): Page No: 186 - 194 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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