A Review on Levodopa/Carbidopa drug for treatment of Parkinson’s Disease

Saurabh N. Bodkhe , Omprasad R. Deshmukh , Prof.Pavan N. Folane , Dr. R.H. Kale , Dr.K.R.Biyani

Parkinson’s disease, Levodopa/ Carbidopa, complication, Dyskinesia, motor fluctuation, Levodopa therapy

Parkinson’s Disease is a common movement disorder seen in neurological practice, but the diagnosis and management is challenging. The diagnosis is clinical and sometimes difficult, considering a large number of motor and non-motor symporters in PD patients is difficult, as choices of drugs are limited and levodopa is the mainstay of treatment. However, Levodopa- induced dyskinesia (LID) is commonly seen in Parkinson’s disease patients treated with levodopa, this side effect is usually encountered after a long duration of treatment, but occasionally.This may be seen after a few days or months of treatment. Levodopa a dopamine precursor is an effective and well tolerated dopamine replacement agents used to treat PD. The clinical use of levodopa may eventually be limited by the development of various treatment related complications, Including response fluctuations and psychiatric s, poor bioavailability, narrow therapeutic window are all crucial for such fluctuations. Levodopa remains the most potent dopaminergic therapy for PD.

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"A Review on Levodopa/Carbidopa drug for treatment of Parkinson’s Disease", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.5, Issue 9, page no.478 - 483, September-2020, Available :https://ijsdr.org/papers/IJSDR2009079.pdf

Volume 5 Issue 9, September-2020

Pages : 478 - 483

Paper Reg. ID: IJSDR_192512

Published Paper Id: IJSDR2009079

Downloads: 000347189

Research Area: Engineering

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Published Paper PDF: https://ijsdr.org/papers/IJSDR2009079

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2009079

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

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