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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | EVALUATION OF IMMUNOMODULATORY POTENTIAL OF PHYLLANTHUS EMBLICA FRUIT EXTRACT IN WISTAR RATS |
| Authors Name: | S. ANITHA KUMARI , P. MADHUSUDHANA CHARY |
| Unique Id: | IJSDR2212186 |
| Published In: | Volume 7 Issue 12, December-2022 |
| Abstract: | In the present study, the aqueous fruit extract of Phyllanthus emblica was evaluated for its immunomodulatory effect on the male wistar rats. The rats were divided into three groups. The first group received normal saline and served as control whereas the groups II and III received aqueous fruit extract of Phyllanthus emblica at a dose of 100 and 200mg/kg body weight/day respectively for 21 days. A significant increase was observed in the total leucocyte count, lymphocyte %, serum total protein, serum globulin and serum albumin in the treated rats in a dose-dependent manner when compared to the control rats. The treated group also exhibited an increase in the relative weight of the spleen. Further, Phyllanthus emblica treated rats (group II and III) also showed significant antibody titre values and DTPH reaction when compared to the control group thus indicating its ability to stimulate the humoral as well as cell mediated immunity. |
| Keywords: | Phyllanthus emblica, Rats, Immunomodulatory, humoral immunity, cell-mediated immunity |
| Cite Article: | "EVALUATION OF IMMUNOMODULATORY POTENTIAL OF PHYLLANTHUS EMBLICA FRUIT EXTRACT IN WISTAR RATS", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 12, page no.1154 - 1158, December-2022, Available :http://www.ijsdr.org/papers/IJSDR2212186.pdf |
| Downloads: | 000337070 |
| Publication Details: | Published Paper ID: IJSDR2212186 Registration ID:203189 Published In: Volume 7 Issue 12, December-2022 DOI (Digital Object Identifier): Page No: 1154 - 1158 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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