INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Antioxidant and Antidiabetic Activity of Phyllanthus Emblica Fruit Extract in Wistar Rats
Authors Name:
S. ANITHA KUMARI
, P. MADHUSUDHANACHARY
Unique Id:
IJSDR2301160
Published In:
Volume 8 Issue 1, January-2023
Abstract:
The present study was performed to assess the antioxidant and antidiabetic activity of Phyllanthus emblica fruit extract. The antioxidant activity was carried out in different concentrations of aqueous fruit extract using DPPH assay. The aqueous fruit extract of Phyllanthus emblica exhibited more scavenging activity of DPPH in a dose-dependent manner when compared to the control. The antidiabetic activity of Phyllanthus emblica fruit extract was studied in male wistar rats. The rats were divided into 5 groups. Group I served as the control group. Group II was rendered diabetic through intraperitoneal injection of streptozotocin (60mg/Kg body weight) .Group III received aqueous fruit extract of Phyllanthus emblica (200mg/kg body weight) daily through oral gavage for 28 days. Group IV rats received glibenclamide (600µg/Kg body weight) daily through oral gavage for 28 days and group V received only the aqueous fruit extract of Phyllanthus emblica. The study revealed a significant increase in the blood glucose levels and a decrease in the plasma insulin levels in the diabetic rats when compared to the control rats indicating the antidiabetic activity of Phyllanthus emblica fruit extract. The study suggests that Phyllanthus emblica fruit extract can be recommended for use as a natural supplementary herbal remedy to the diabetic patients.
"Antioxidant and Antidiabetic Activity of Phyllanthus Emblica Fruit Extract in Wistar Rats", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 1, page no.1005 - 1009, January-2023, Available :http://www.ijsdr.org/papers/IJSDR2301160.pdf
Downloads:
000337077
Publication Details:
Published Paper ID: IJSDR2301160
Registration ID:203520
Published In: Volume 8 Issue 1, January-2023
DOI (Digital Object Identifier):
Page No: 1005 - 1009
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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