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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH
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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Paper Title: A Cross Sectional Study On Diagnostic Findings And Treatment Between Children And Adults Based On KDIGO Guidelines Of Nephrotic Syndrome
Authors Name: Dr. K. Krupa Jacinth* , B.Heena , G.Supriya , M.Renuka , N.Mounica
Unique Id: IJSDR2301185
Published In: Volume 8 Issue 1, January-2023
Abstract: Aim and objectives: The aim of our study is, to study the clinical profile, investigation profile and treatment plan in children and adults with nephrotic syndrome according to KDIGO GUIDELINES. Methods: This is a Prospective Observational Study and the subjects involved are the patients visiting a pediatric department and nephrology department, diagnosed with a nephrotic syndrome and with relapses. All the data of the subjects are collected by using the case proforma and the data collection includes demographic details, past medical history, past medication history, history investigations, personal habits, allergies, diagnosis, laboratory investigations and drug prescribed. Results: In our study a total of 99 subjects were recruited among those paediatrics were 45 and adults were 54. On biochemical examination the sr. albumin profile shows hypoalbuminemia the major hypoalbuminemia range is found among paediatrics N=45 with mean of 15 ie., >0.6mg/dl- 37(82.2%), followed by 0.2-0.6mg/dl -7 (15.5%), <0.2mg/dl-1 (2.2%) and adults N=54 with mean of 18 major hypoalbuminemia found at >0.6mg/dl -39(72.2%), followed by 0.2-0.6mg/dl-13 (24%), and <0.2-2 (3.7%) On urine examination frothy appearance of urine was observed in almost patients of paediatrics and adults. Main treatment includes managing edema: Lasix; hypertension: nefidipine, enalapril, amlodipine, betablockers, telmisartan; corticosteroid therapy: tab.prednisolone, inj.methyl prednisolone; immunosuppressant: methotrexate, sulfasalazine, hydroxychloroquine, azathioprine; antibiotics: ceftriaxone, doxycycline, amoxyclav, other antibiotics; alkalysing agent: sodium bicarbonate; antacids: ranitidine;PPIs: pantoprazole. Conclusion:- Our study concluded that, most of the children are with minimal change disease but in adults none were observed with MCD .Most of the adults are diagnosed with secondary cause (FSGS).In adults mostly in females lupus nephritis were observed .Hypertension is one of the complication mostly seen in pediatrics.
Keywords: Key Words: KDIGO, Nephrotic syndrome, MCD, FSGS, PPI, Department of pharmacy practice, CESCOP.
Cite Article: "A Cross Sectional Study On Diagnostic Findings And Treatment Between Children And Adults Based On KDIGO Guidelines Of Nephrotic Syndrome", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 1, page no.1163 - 1179, January-2023, Available :http://www.ijsdr.org/papers/IJSDR2301185.pdf
Downloads: 000336256
Publication Details: Published Paper ID: IJSDR2301185
Registration ID:203741
Published In: Volume 8 Issue 1, January-2023
DOI (Digital Object Identifier):
Page No: 1163 - 1179
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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