|
INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
Imp Links for Author
Imp Links for Reviewer
Research Area
Subscribe IJSDR
Visitor Counter
Copyright Infringement Claims
Indexing Partner
|
Published Paper Details
|
|
| Paper Title: | 5-HYDROXY PYRAZOLE DERIVATIVE AS AN ANTIHYPERLIPIDEMIC AGENT: DESIGN, SYNTHESIS AND EVALUATION WITH NPC1L1 INHIBITORY ACTIVITY |
| Authors Name: | Radhika Kasera , Dr. Neha Kawathekar |
| Unique Id: | IJSDR2303109 |
| Published In: | Volume 8 Issue 3, March-2023 |
| Abstract: | In order to investigate the SAR of 5-hydroxy pyrazole analogs for the cholesterol absorption inhibitors, electron- donating group were introduced to the C-(4) carbon chain of the 5-hydroxy pyrazole derivative. Nine new derivatives of the 5- hydroxy pyrazole for the cholesterol absorption inhibitor have been synthesized. All the synthesized new compounds were evaluated for the activity to inhibit cholesterol absorption in hamster and above all of them some showed comparable good effects in suppressing the level of total cholesterol in the blood. |
| Keywords: | Antihyperlipidemia, 5-hydroxy pyrazole, Docking, NPC1L1, Cholesterol absorption inhibitor. |
| Cite Article: | "5-HYDROXY PYRAZOLE DERIVATIVE AS AN ANTIHYPERLIPIDEMIC AGENT: DESIGN, SYNTHESIS AND EVALUATION WITH NPC1L1 INHIBITORY ACTIVITY", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 3, page no.674 - 682, March-2023, Available :http://www.ijsdr.org/papers/IJSDR2303109.pdf |
| Downloads: | 000337074 |
| Publication Details: | Published Paper ID: IJSDR2303109 Registration ID:204493 Published In: Volume 8 Issue 3, March-2023 DOI (Digital Object Identifier): Page No: 674 - 682 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijsdr.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
Track Paper
Important Links
Conference Proposal
ISSN
 |
 |
DOI (A digital object identifier)
  Providing A digital object identifier by DOI How to GET DOI and Hard Copy Related |
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
 |
 |
 |
Social Media
Indexing Partner |
|||
| Copyright © 2024 - All Rights Reserved - IJSDR | |||
Facebook Twitter Instagram LinkedIn