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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | A STUDY ON ANATOMIC LOCALIZATION PATTERN AND MORPHOLOGICAL FEATURES OF PULMONARY MULTIPLE NODULES AND ITS CORRELATION WITH LUNG DISEASES BY HRCT EVALUATION |
| Authors Name: | Soorya Prakash , Sunder. K , Vishaka Mazumder |
| Unique Id: | IJSDR2303169 |
| Published In: | Volume 8 Issue 3, March-2023 |
| Abstract: | BACKGROUND: The Fleischner Society's Nomenclature Committee has described a lung nodule as a rounded or irregular opacity that is well or poorly defined and measuring up to 3 cm in size. The lung is made up of network of connective tissue fibers called lung interstitium. Important subsegmental lung units are lung acinus and secondary pulmonary lobule. Pulmonary nodules are distributed in relation to the secondary lobule and have a significant role in the diagnosis of diffuse multinodular disorders. Assessment of the distribution of multiple pulmonary nodules has been a crucial step in the diagnostic process in High resolution CT scan (HRCT) evaluation. The Aim of this study is to assess HRCT anatomic Localization and morphological characters of multiple pulmonary nodules and its correlation with specific lung disease. MATERIALS AND METHODS: A prospective observational study was conducted with HRCT images of 75 patients with known diagnosis were evaluated by using Multinodular HRCT algorithm. Nodules were placed into four anatomic locations: perilymphatic, random, centrilobular with tree in bud opacity and cetrilobular nodule without tree in bud opacity. Algorithm accuracy was assessed by comparing the anatomic location to that expected location for each specific disease on the basis of reports in the literature. RESULT: In this study with nodule localization, 24 out of 25 Pulmonary tuberculosis cases had centrilobular nodule with tree in bud opacity distribution pattern with a concordance rate of 96% 12 out of 14 sarcoidosis cases had perilymphatic distribution with a concordance rate of 86%. 5 cases miliary tuberculosis cases had random distribution pattern with the concordance rate of 100%, 9 out of 10 bacterial infection cases had centrilobular nodule with tree in bud opacity distribution pattern with a concordance rate of 90%. 3 out of 4 fungal infection cases had centrilobular nodule with tree in bud opacity distribution pattern with a concordance rate of 75% 7 out of 10 metastatic disease had random distribution pattern with a concordance rate of 70% 3 hypersensitivity pneumonitis cases had centrilobular nodule without tree in bud opacity with a concordance rate of 100%. CONCLUSION: We conclude that this algorithm is accurate with the anatomic nodule location as expected with patient final diagnosis, reproducible and reliable in Indian population. |
| Keywords: | Multiple nodules, Pulmonary Tuberculosis, Centrilobular Nodules, Perilymphatic Nodules. |
| Cite Article: | "A STUDY ON ANATOMIC LOCALIZATION PATTERN AND MORPHOLOGICAL FEATURES OF PULMONARY MULTIPLE NODULES AND ITS CORRELATION WITH LUNG DISEASES BY HRCT EVALUATION", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 3, page no.1021 - 1028, March-2023, Available :http://www.ijsdr.org/papers/IJSDR2303169.pdf |
| Downloads: | 000337074 |
| Publication Details: | Published Paper ID: IJSDR2303169 Registration ID:204687 Published In: Volume 8 Issue 3, March-2023 DOI (Digital Object Identifier): Page No: 1021 - 1028 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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