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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Role of Magnetic Resonance Imaging in Early Progressive Dementia in diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) |
| Authors Name: | Mahender Reddy Yasa , Manasa Ravipati , Sudhakar Katojju |
| Unique Id: | IJSDR2303172 |
| Published In: | Volume 8 Issue 3, March-2023 |
| Abstract: | Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is an autosomal dominant vascular disorder. Diagnosis and follow-up in patients with CADASIL are based mainly on magnetic resonance imaging (MRI). MRI shows white matter hyperintensities (WMHs). WMHs lesions tend to be symmetrical and bilateral, distributed in the periventricular and deep white matter. The anterior temporal lobe and external capsules are predilection sites for WMHs, with higher specificity and sensitivity of anterior temporal lobe involvement compared to an external capsule involvement. Lacunar infarcts are presented by an imaging signal that has intensity of cerebrospinal fluid in all MRI sequences. They are localized within the semioval center, thalamus, basal ganglia and pons. CMBs are depicted as focal areas of signal loss on T2 images which increases in size on the T2*-weighted gradient echo planar images (“blooming effect”). |
| Keywords: | CADASIL, MRI, computed tomography, white matter hyperintensities, cerebral microbleeds. |
| Cite Article: | "Role of Magnetic Resonance Imaging in Early Progressive Dementia in diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 3, page no.1040 - 1042, March-2023, Available :http://www.ijsdr.org/papers/IJSDR2303172.pdf |
| Downloads: | 000337070 |
| Publication Details: | Published Paper ID: IJSDR2303172 Registration ID:204724 Published In: Volume 8 Issue 3, March-2023 DOI (Digital Object Identifier): Page No: 1040 - 1042 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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