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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH
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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Paper Title: Delta Albumin A Game Changer In Predicting Adverse Surgical Outcomes In Open Abdominal Surgeries
Authors Name: Dr Shalvi Pohekar , Dr Sudhir M , Dr Suraj S K , Dr Girish HR
Unique Id: IJSDR2305348
Published In: Volume 8 Issue 5, May-2023
Abstract: Delta Albumin A Game Changer In Predicting Adverse Surgical Outcomes In Open Abdominal Surgeries Introduction Albumin is an important protein; it is considered a negative active phase protein. In spite of other factors predicting surgical outcomes, little is known about the perioperative dynamics of Albumin and its effect on surgical outcome in abdominal surgeries. Delta albumin is calculated using Preoperative Serum Albumin (PreOD) and Postoperative day 1 S. Albumin (POD1). Aim This study is aimed to explore perioperative serum Albumin as a predictor of adverse outcome in open abdominal surgeries. Objective To assess the effect of pre and post-operative serum Albumin on postoperative complications by calculating the percentage decrease in serum Albumin (Delta Albumin). Delta Albumin = (𝑃𝑟𝑒𝑂𝐷 −𝑃𝑂𝐷1)/𝑃𝑟𝑒𝑂𝐷 x 100. Methods Preoperative Serum Albumin (PreOD) and Postoperative day 1 S. Albumin (POD1) of 60 patients undergoing Emergency open Abdominal surgery was analyzed and Delta albumin calculated. Cutoff for delta albumin (13.51%) was obtained by ROC curve analysis for the occurrence of postoperative complications. All patients were followed up for 30 days post surgery for adverse surgical outcomes like: Surgical site infection, delayed wound healing, anastomotic leak, enterocutaneous fistula formation, need for reoperation, shock and death. These were graded with Clavien-Dindo classification. Results Delta albumin cutoff for post-operative complications was 13.51 % Patients with delta albumin below 13.51% did not develop post-operative complication (Specificity : 100%). Patients with delta albumin above 13.51% developed one or more of the mentioned complications within 30 days of surgery (Sensitivity 78.1%). Conclusion This study concluded that a percentage decrease of serum albumin perioperatively (Delta Albumin) is a better predictor of postoperative adverse outcomes in patients undergoing open abdominal surgeries than Serum Albumin (both pre and post-operative). Hence Delta albumin can be used as a simple, low-cost prognostic tool to predict the risk of adverse surgical outcomes.
Keywords: Delta albumin, Albumin, Postoperative complications, Open abdominal surgeries, Adverse surgical outcome
Cite Article: "Delta Albumin A Game Changer In Predicting Adverse Surgical Outcomes In Open Abdominal Surgeries ", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 5, page no.2200 - 2206, May-2023, Available :http://www.ijsdr.org/papers/IJSDR2305348.pdf
Downloads: 000336256
Publication Details: Published Paper ID: IJSDR2305348
Registration ID:206436
Published In: Volume 8 Issue 5, May-2023
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.36204
Page No: 2200 - 2206
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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