|
INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
Imp Links for Author
Imp Links for Reviewer
Research Area
Subscribe IJSDR
Visitor Counter
Copyright Infringement Claims
Indexing Partner
|
Published Paper Details
|
|
| Paper Title: | The role of ACE II receptor gene polymorphism in outcome of COVID 19 in Chhattisgarh population |
| Authors Name: | M MANISH |
| Unique Id: | IJSDR2305370 |
| Published In: | Volume 8 Issue 5, May-2023 |
| Abstract: | A novel coronavirus designated as SARS-CoV-2 emerged in the city of Wuhan, China, and caused an outbreak of unusual viral pneumonia. Transmission of COVID-19 is mainly caused by respiratory droplets and prominently affect the respiratory tract (both lower and upper respiratory tract). SARS-CoV-2 infection necessitates the binding of the virus to the membrane-bound form of angiotensin-converting enzyme 2 (ACE2) receptor and internalization of the complex by the host cell so aim of study to assess ACE 2 polymorphisms can alter host susceptibility to SARS-CoV-2 by affecting this interaction and have assessed the outcome. It is Hospital based, Observational, Case Control study, in which 9 cases and 9 controls total 18 subjects were enrolled retrospectively in 10 months All subjects where COVID positive detected by RT-PCR. All cases were genotyped for ACE 2 I/D polymorphism using polymerase chain reaction We had observered that presence of genotype (DD) are exposed group of patients as these genotypes were predicted as severe form of COVID 19 infections and was found in 44% (4/9) among cases and 14% (1/9) among control groups (OR:6.40).These data suggest that the ACE 2 genotype may impact the incidence and clinical outcome of COVID-19 and serve as a predictive marker for COVID-19 risk and severity. |
| Keywords: | ACE II receptor, COVID 19,I & D Polymorphism,RT-PCR,SARS-COV-2 |
| Cite Article: | "The role of ACE II receptor gene polymorphism in outcome of COVID 19 in Chhattisgarh population", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 5, page no.2342 - 2345, May-2023, Available :http://www.ijsdr.org/papers/IJSDR2305370.pdf |
| Downloads: | 000337078 |
| Publication Details: | Published Paper ID: IJSDR2305370 Registration ID:205902 Published In: Volume 8 Issue 5, May-2023 DOI (Digital Object Identifier): Page No: 2342 - 2345 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijsdr.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
Track Paper
Important Links
Conference Proposal
ISSN
 |
 |
DOI (A digital object identifier)
  Providing A digital object identifier by DOI How to GET DOI and Hard Copy Related |
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
 |
 |
 |
Social Media
Indexing Partner |
|||
| Copyright © 2024 - All Rights Reserved - IJSDR | |||
Facebook Twitter Instagram LinkedIn