1,3,4- Oxadiazole: A Therapeutical Emerging Scaffold

Geetanjali Mehara , Kumud Upadhyaya , Amita Joshi Rana

Anti-inflammation, Anti-cancer, Anti-arrhythmic, Heterocyclic ring, Anticonvulsant, 1,3,4-Oxadiazole

The five-membered heterocyclic ring oxadiazole symbolizes the significance of a structural key in pharmaceutical and medicinal chemistry. Four distinct isomers of oxadiazole exist 1,2,3-oxadiazole, 1,2,5-oxadiazole, 1,3,4-oxadiazole and 1,2,4-oxadiazole. Due to their extensive spectrum of chemical and biological properties, the 1,3,4-oxadiazole and 1,2,4-oxadiazole are better and are extensively investigated by researchers. The aromatic heterocyclic 1,3,4-oxadiazole has two nitrogen and one oxygen in its nucleus. The nucleus of the 1,3,4-oxadiazole is a biological scaffold with a wide range of pharmacological activities such as anti-cancer, anti-inflammation, analgesic, anti-HIV, anti-bacterial, anti-hypertensive, anti-tubercular, ant-microbial, anti-helminthic, anti-oxidant, anti-diabetic, anti-viral, anti-parkinsonian and anti-convulsant etc. The 1,3,4-oxadiazole scaffold is present in many marketed formulations such as nitrofuran derivative (Furamizole) which has potent anti-bacterial activity, Raltegrav

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"1,3,4- Oxadiazole: A Therapeutical Emerging Scaffold", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 9, page no.1022 - 1033, September-2023, Available :https://ijsdr.org/papers/IJSDR2309149.pdf

Volume 8 Issue 9, September-2023

Pages : 1022 - 1033

Paper Reg. ID: IJSDR_208655

Published Paper Id: IJSDR2309149

Downloads: 000347169

Research Area: Pharmacy

Country: Almora, uttarakhand, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2309149

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2309149

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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