INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Life Cycle Management of Analytical RP-HPLC Method Development for Assay of Abilify Discmelt in Immediate Release Dosage Form
Authors Name:
Mr. Avinash M. Bhagwat
, Dr. Rahul V. Mayee , Dr. Ajit B. Ekal
Unique Id:
IJSDR2207086
Published In:
Volume 7 Issue 7, July-2022
Abstract:
In this research work of life cycle management of analytical RP-HPLC method development for assay of Abilify Discmelt in immediate release dosage form, the RP-HPLC assay method was developed and validated for Abilify Discmelt. Stress study is also carried out. The chromatographic conditions will be as, mobile phase is 0.05M Phosphate buffer pH2.0, Methanol, Acetonitrile in a ratio of 5:3:2, column used is Hypersil ODS C-18, 250 mm x 4.6 mm, 5.0 mm, Flow Rate1.5 ml/min, Injection volume 20 µl, Detection wavelength is 215 nm and run time is 25 min. This life cycle management stability indicating RP-HPLC analytical method is economical, specific, accurate, precise and robust for assay of Abilify Discmelt in immediate release dosage form.
Keywords:
Abilify Discmelt, Life Cycle Management, RP-HPLC Method Development, Validation, Immediate Release Dosage Form
Cite Article:
"Life Cycle Management of Analytical RP-HPLC Method Development for Assay of Abilify Discmelt in Immediate Release Dosage Form", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 7, page no.584 - 594, July-2022, Available :http://www.ijsdr.org/papers/IJSDR2207086.pdf
Downloads:
000338719
Publication Details:
Published Paper ID: IJSDR2207086
Registration ID:200921
Published In: Volume 7 Issue 7, July-2022
DOI (Digital Object Identifier):
Page No: 584 - 594
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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