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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Recent advances in cyclodextrin based transdermal drug delivery |
| Authors Name: | Neha Chauhan , Sahil Singh , Manpreet kaur walia |
| Unique Id: | IJSDR2308071 |
| Published In: | Volume 8 Issue 8, August-2023 |
| Abstract: | This review addresses case studies incorporating hydro gel, gel patch, micro needles, and liposome micro emulsion to provide a thorough overview of current developments in Cyclodextrins-based transdermal drug delivery. Cyclodextrins have emerged as adaptable excipients with the potential to improve medication transport over the skin as transdermal drug delivery has grown in popularity as a non-invasive and patient-friendly route of administration. The case studies examine how Cyclodextrins are included into each delivery system and look at how they affect the drug's solubility, stability, and permeability. In particular, the addition of cyclodextrin into hydro gel formulations exhibits improved drug penetration and sustained release characteristics, whereas gel patches accomplish controlled drug release and extended skin residence. Drug distribution that is precise and targeted is made possible by integration with micro needles thanks to the development of inclusion complexes. Additionally, better drug encapsulation and release properties are shown by cyclodextrin-stabilized liposome micro emulsions. The paper also discusses production issues and safety concerns, offering insightful information on how cyclodextrin-based transdermal drug delivery systems may revolutionize medication administration for better therapeutic results. |
| Keywords: | Cyclodextrin, Transdermal Drug Delivery System, Hydrogel, Microneedles, Patch |
| Cite Article: | "Recent advances in cyclodextrin based transdermal drug delivery", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 8, page no.490 - 498, August-2023, Available :http://www.ijsdr.org/papers/IJSDR2308071.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2308071 Registration ID:208175 Published In: Volume 8 Issue 8, August-2023 DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.35858 Page No: 490 - 498 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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