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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | ACUTE AND SUB ACUTE DERMAL TOXICITY OF SIDDHA FORMULATION - NUNAPATTAI THAILAM |
| Authors Name: | RAHUL M , SIMAL S , GNANASEKAR D |
| Unique Id: | IJSDR2309113 |
| Published In: | Volume 8 Issue 9, September-2023 |
| Abstract: | Nunapattaithailam (NPT) is being used to treat various skin ailments including Atopic dermatitis. This study aims to investigate the acute & sub Acute dermal toxicity of NPT following single repeated doses of exposure. A group of 24 Adult rats ie. 4 groups (n=6per group) for both acute & sub acute dermal toxicity. The duration for each study is determined to be 14 days for Aute toxicity and 28 days for subacute toxicity. The rats were Applied with the liquid test substance on the shaved area of dorsal surface of the trunk of the test Animal. For Acute toxicity the rats in both groups recieved the application of the liquid test substance on the first day of the study, and the rats in subacute toxity were given the liquid test Substance for 28 days. Throughout the study period all the rats were observed for changes in physical, Appearance & Behavioural pattern observed to All the rats. Body Weight, Haematology,serum Biochemistry result shows no significant changes in both groups Thus this study indicates that the tropical application of NPT dose not induce any aute & subacute adverse effects on the skin or systemic toxic reactions in Rats. |
| Keywords: | Dermal toxicity, Nunapattai thailam,Haematology,Liver enzymes,Histology. |
| Cite Article: | "ACUTE AND SUB ACUTE DERMAL TOXICITY OF SIDDHA FORMULATION - NUNAPATTAI THAILAM ", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 9, page no.742 - 745, September-2023, Available :http://www.ijsdr.org/papers/IJSDR2309113.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2309113 Registration ID:208489 Published In: Volume 8 Issue 9, September-2023 DOI (Digital Object Identifier): Page No: 742 - 745 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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