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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | A Comprehensive Review of COVID-19 Patients with Pre-Existing Cardiovascular Diseases Receiving an Anticoagulant Therapy |
| Authors Name: | Karthick.K , Sree Janardhanan. |
| Unique Id: | IJSDR2312032 |
| Published In: | Volume 8 Issue 12, December-2023 |
| Abstract: | The emergence of COVID-19 has significantly impacted individuals with pre-existing cardiovascular diseases (CVD), presenting challenges in managing the disease due to increased thrombotic events. Anticoagulant therapy has been extensively explored as a potential intervention to mitigate the hypercoagulable state observed in severe COVID-19 cases. This comprehensive review aims to evaluate the outcomes and efficacy of anticoagulant therapy in COVID-19 patients with pre-existing CVD. A systematic literature search was conducted across multiple databases to identify relevant studies published between December 2019 and January 2023. Eligible studies included clinical trials, retrospective analyses, and observational studies focusing on COVID-19 patients with prior CVD who received anticoagulant therapy. The review highlights the diverse spectrum of anticoagulant agents employed, including heparins, direct oral anticoagulants (DOACs), and antiplatelet therapies, outlining their respective efficacy and safety profiles in this patient population. Additionally, the impact of anticoagulation on clinical outcomes such as mortality, thrombotic events, and bleeding complications is critically assessed. However, challenges persist regarding the optimal dosing strategies, duration of therapy, and the risk-benefit ratio of anticoagulation, necessitating further prospective studies and randomized controlled trials for precise guidelines and recommendations. In conclusion, anticoagulant therapy demonstrates potential benefits in COVID-19 patients with pre-existing CVD, exhibiting a favourable impact on clinical outcomes. Nevertheless, a nuanced approach considering individual patient characteristics and disease severity is imperative for optimizing antithrombotic strategies and enhancing patient care amidst the ongoing pandemic. |
| Keywords: | cardiovascular diseases, COVID-19, anticoagulant therapy. |
| Cite Article: | "A Comprehensive Review of COVID-19 Patients with Pre-Existing Cardiovascular Diseases Receiving an Anticoagulant Therapy", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 12, page no.230 - 234, December-2023, Available :http://www.ijsdr.org/papers/IJSDR2312032.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2312032 Registration ID:209518 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: 230 - 234 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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