INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
A Review On Delivering Drugs Through The Skin: A Thorough Exploration of Transdermal Systems
Authors Name:
Kishor Chandrakant Badgujar
, Balaprasad Parmeshwar Borade , Shital R. Rajput , Kalpesh S. More , Kalpeshkumar S. Wagh
Unique Id:
IJSDR2312045
Published In:
Volume 8 Issue 12, December-2023
Abstract:
Transdermal drug delivery systems have come a long way from their inception, evolving into a critical component of modern medicine. This review provides a comprehensive exploration of the various aspects surrounding transdermal drug delivery. It begins with an introduction, defining and delving into the historical development of transdermal patches. The advantages of this drug delivery method, including painless administration, sustained release, and avoidance of first-pass metabolism, are discussed, along with the inherent limitations, such as restrictions on drug types, skin permeability issues, and size constraints. The mechanisms of transdermal delivery, encompassing passive diffusion and active transport, are detailed, shedding light on the key factors affecting skin permeability and drug absorption rates. Transdermal patch design, incorporating different types and materials, is explained, along with drug selection criteria and formulation considerations. The importance of adhesive technology in ensuring patch adherence, skin compatibility, and wearability is highlighted.
Keywords:
Transdermal delivery, skin penetration, Permeation enhancer, Mechanisms of Transdermal system, Application of Transdermal systems.
Cite Article:
"A Review On Delivering Drugs Through The Skin: A Thorough Exploration of Transdermal Systems", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 12, page no.324 - 330, December-2023, Available :http://www.ijsdr.org/papers/IJSDR2312045.pdf
Downloads:
000338719
Publication Details:
Published Paper ID: IJSDR2312045
Registration ID:209529
Published In: Volume 8 Issue 12, December-2023
DOI (Digital Object Identifier):
Page No: 324 - 330
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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