|
INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
Imp Links for Author
Imp Links for Reviewer
Research Area
Subscribe IJSDR
Visitor Counter
Copyright Infringement Claims
Indexing Partner
|
Published Paper Details
|
|
| Paper Title: | DIFFUSION TENSOR IMAGING IN CHILDREN WITH DEVELOPMENTAL DELAY |
| Authors Name: | Dr Anish Chakravarty , Dr Gautam Muthu |
| Unique Id: | IJSDR2312060 |
| Published In: | Volume 8 Issue 12, December-2023 |
| Abstract: | ABSTRACT: Purpose: To determine whether diffusion-tensor magnetic resonance (MR) imaging can depict abnormalities in patients with a diagnosis of developmental delay but structurally normal brain MR imaging results. Materials and methods: Thirty paediatric patients who received a diagnosis of developmental delay underwent brain MR examinations, including diffusion-tensor MR imaging. The MR findings in these patients were compared with those in 30 age-matched neurodevelopmentally healthy children. Mean diffusivity (MD) and anisotropy (FA) were measured bilaterally in regions of interest in anterior and posterior limbs of internal capsule, forceps minor and forceps major, pre and postcentral gyrus, frontal and temporal white matter, and genu, body & Splenium of corpus callosum. By using a one-tailed Student t test in the positive direction for MD and in the negative direction for anisotropy and P <0.05 to indicate a significant difference, the MD and FA values for children with developmental delay were compared with those for children who were neurodevelopmentally healthy. Results: The results of our study revealed that there was a significant reduction in FA values in children with developmental delay, when compared to controls, mapped P values at genu of corpus callosum, body of corpus callosum, splenium of corpus callosum, right anterior limb of internal capsule, left anterior limb of internal capsule, right posterior limb of internal capsule, left posterior limb of internal capsule, right forceps minor, left forceps minor, left forceps major, left precentral gyri, right postcentral gyri, right frontal lobe white matter, left temporal lobe white matter and left temporal lobe white matter (p < 0.005). Also, there was significant increase in MD values in genu of corpus callosum, body of corpus callosum, right anterior limb of internal capsule, left anterior limb of internal capsule, right forceps minor, left forceps major, right postcentral gyri, left postcentral gyri, left frontal lobe white matter, left temporal lobe white matter respectively (p < 0.005). Conclusion: In the children with developmental delay, diffusion-tensor MR imaging depicted decreases in anisotropy and increases in FA in the white matter fiber tracts, which appeared to be normal at conventional MR imaging. |
| Keywords: | Anisotropy, Children, Corpus callosum, Developmental delay, DTI, MRI |
| Cite Article: | "DIFFUSION TENSOR IMAGING IN CHILDREN WITH DEVELOPMENTAL DELAY", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 12, page no.441 - 450, December-2023, Available :http://www.ijsdr.org/papers/IJSDR2312060.pdf |
| Downloads: | 000338721 |
| Publication Details: | Published Paper ID: IJSDR2312060 Registration ID:209579 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: 441 - 450 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijsdr.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
Track Paper
Important Links
Conference Proposal
ISSN
 |
 |
DOI (A digital object identifier)
  Providing A digital object identifier by DOI How to GET DOI and Hard Copy Related |
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
 |
 |
 |
Social Media
Indexing Partner |
|||
| Copyright © 2024 - All Rights Reserved - IJSDR | |||
Facebook Twitter Instagram LinkedIn