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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Peptide Drug Conjugates : A new hope to improve Cancer Management |
| Authors Name: | Mr.Kamlesh S Pathak , Dr.Santosh Jain , Ms.P.M.Raut |
| Unique Id: | IJSDR2312092 |
| Published In: | Volume 8 Issue 12, December-2023 |
| Abstract: | Cancer remains the leading cause of death worldwide despite advances in treatment options for patients. As such, safe and effective therapeutics are required. Short peptides provide advantages to be used in cancer management due to their unique properties, amazing versatility, and progress in biotechnology to overcome peptide limitations. Several appealing peptide- based therapeutic strategies have been developed. Here, we provide an overview of peptide conjugates, the better equivalents of antibody-drug conjugates, as the next generation of drugs for required precise targeting, enhanced cellular permeability, improved drug selectivity, and reduced toxicity for the efficient treatment of cancers. We discuss the basic components of drug conjugates and their release action, including the release of cytotoxins from the linker. We also present peptide-drug conjugates under different stages of clinical development as well as regulatory and other challenges. |
| Keywords: | short peptides; peptide-drug conjugates; drug delivery; cancer; Linkers; nanotechnology |
| Cite Article: | "Peptide Drug Conjugates : A new hope to improve Cancer Management", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 12, page no.710 - 715, December-2023, Available :http://www.ijsdr.org/papers/IJSDR2312092.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2312092 Registration ID:209631 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: 710 - 715 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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