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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | A Review on the tumour immune microenvironment and the emergence of mRNA vaccines as a novel therapeutic strategy |
| Authors Name: | Advay Gupta , Matthew Hill |
| Unique Id: | IJSDR2401002 |
| Published In: | Volume 9 Issue 1, January-2024 |
| Abstract: | Cancer is the second leading cause of death in the world. The immune system has been shown to be a critical regulator of tumour development through clearance and via the process of immunoediting, by which cancers will dampen the immune response to promote their progression. The advent of immunotherapies has become a revolutionary treatment as it uses the nature of the immune system to fight back at cancers. This review will focus on the pivotal role of the tumour microenvironment in tumour progression and tumour-immune dynamics, through cellular signalling, gene expression and cell-cell interactions. Subsequently, an overview of current immunotherapies will be presented and evaluated. Finally, this review will present mRNA vaccines as a novel therapeutic strategy and determine their implications for cancer treatment. |
| Keywords: | Cancer, Immunology, mRNA vaccines |
| Cite Article: | "A Review on the tumour immune microenvironment and the emergence of mRNA vaccines as a novel therapeutic strategy", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 1, page no.13 - 26, January-2024, Available :http://www.ijsdr.org/papers/IJSDR2401002.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2401002 Registration ID:209718 Published In: Volume 9 Issue 1, January-2024 DOI (Digital Object Identifier): Page No: 13 - 26 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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