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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Method to boost solubility |
| Authors Name: | Vaishnavi Bhaskar Borgaonkar , Achal Harinarayan Yelane |
| Unique Id: | IJSDR2401059 |
| Published In: | Volume 9 Issue 1, January-2024 |
| Abstract: | The process of a solid dissolving in a liquid phase to create a homogenous mixture is known as solubility. A crucial factor in getting the right quantity of drug into the bloodstream to show a pharmacological effect is solubility. Low water solubility of the novel therapeutic compound is the main issue with formulation. Poorly aqueous soluble medications need substantial dosages to reach their maximum therapeutic plasma concentration after oral delivery. Using the biopharmaceutical classification system (BCS), substances are categorized according to their solubility and permeability. Regulatory agencies and health organizations have adopted this categorization system to enable dissolution to be used to verify bioequivalence for highly soluble and highly permeable chemicals. Drugs with poor water solubility dissolve slowly, which reduces their bioavailability when taken orally. This review article aims to increase bioavailability and promote efficient absorption. |
| Keywords: | solubility, permeability, bioavailability, biopharmaceutical classification system, absorption. |
| Cite Article: | "Method to boost solubility", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 1, page no.404 - 409, January-2024, Available :http://www.ijsdr.org/papers/IJSDR2401059.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2401059 Registration ID:209869 Published In: Volume 9 Issue 1, January-2024 DOI (Digital Object Identifier): Page No: 404 - 409 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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