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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Role of MRI in Evaluation of Ring Enhancing Lesions of Brain in Correlation with MR Spectroscopy |
| Authors Name: | Dr Chiranth Gowda H P , Dr Gautam Mutu , Dr Anuraj |
| Unique Id: | IJSDR2401075 |
| Published In: | Volume 9 Issue 1, January-2024 |
| Abstract: | Abstract: Introduction: Ring enhancing lesions of the brain though common on neuroimaging are always challenging for radiologists to diagnose because of their varied etiologies. MRI plays a significant role in the early detection and advanced techniques like MR Spectroscopy increase the chances of successful diagnosis by differentiating infectious lesions from non-infectious lesions. Objectives: 1. To establish a differential diagnosis of the various ring enhancing lesions on conventional MRI. 2. To study the characteristic imaging findings of various ring enhancing lesions on MRI. 3. To study the role of MR spectroscopy in the evaluation of various ring enhancing lesions in the brain with a single voxel proton MR spectroscopy. Material and Methods: A prospective observational study was conducted in the Radiology department of a tertiary hospital for a duration of 2 years which included 44 patients. MRI along with MRS was performed on these patients. Results: Among 44 patients, various ring enhancing lesions (REL’s) detected on MRI were tuberculomas (20, 45%) which were the most common followed by, NCC (8, 18%), abscesses (6, 14%), metastases (5, 11%), primary brain tumors (3, 7%) and toxoplasmosis (2, 5%). On MR spectroscopy, Choline peak was observed in 20 (45%) cases, Lipid peak was present in 31 (70%) cases, Lactate peak in 27 (61%) cases reduced NAA peak in 7 (16%) cases and amino acids in 6 (14%) cases. Choline/creatine ratio of <1 was seen in 10 (23%) of the NCC cases, Choline/creatine ratio of >1-2 was seen in 20 (45%) of the NCC cases, Choline/creatine ratio of >2 was seen in 9 (20%) of the NCC cases Conclusion: In this study, MRI and MRS played a pivotal role in successful diagnosis of various ring enhancing lesions which helped in the initiating the treatment among these patients accordingly. |
| Keywords: | Keywords: Choline, Magnetic Resonance Imaging, Metabolites, MRI, MRS, Ring Enhancing Lesions, Tuberculoma. |
| Cite Article: | "Role of MRI in Evaluation of Ring Enhancing Lesions of Brain in Correlation with MR Spectroscopy", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 1, page no.517 - 526, January-2024, Available :http://www.ijsdr.org/papers/IJSDR2401075.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2401075 Registration ID:209917 Published In: Volume 9 Issue 1, January-2024 DOI (Digital Object Identifier): Page No: 517 - 526 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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