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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | ANTIBIOTICS EFFECTS ON PREGNANCY |
| Authors Name: | K.Malleswari , D.Rama Bramha Reddy , G.Samuel Raju |
| Unique Id: | IJSDR2402014 |
| Published In: | Volume 9 Issue 2, February-2024 |
| Abstract: | Background: Limited evidence is available on the safety and efficacy of antimicrobials during pregnancy, with even less according to the trimester of their use. Objective: This study aimed to evaluate the association between exposure to antibiotics therapy (AT) during pregnancy and short-term neonatal outcomes. Methods: We considered 773,237 deliveries that occurred between 2007–2017 in the Lombardy region of Italy. We evaluated the risk of neonatal outcomes among infants that were born to mothers who underwent AT during pregnancy. The odds ratios and the hazard ratios, with the 95% confidence intervals, were estimated respectively for early (first/second trimester) and late (third trimester) exposure. The propensity score was used to account for potential confounders. We also performed subgroup analysis for the class of AT. Results: We identified 132,024 and 76,921 singletons that were exposed to AT during early and late pregnancy, respectively. Infants born to mothers with early exposure had 17, 11, and 16% increased risk of preterm birth, low birth weight, and low Apgar score, respectively. |
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| Cite Article: | "ANTIBIOTICS EFFECTS ON PREGNANCY", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 2, page no.82 - 87, February-2024, Available :http://www.ijsdr.org/papers/IJSDR2402014.pdf |
| Downloads: | 000338722 |
| Publication Details: | Published Paper ID: IJSDR2402014 Registration ID:209972 Published In: Volume 9 Issue 2, February-2024 DOI (Digital Object Identifier): Page No: 82 - 87 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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