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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | GOALS OF COPD TREATEMENT FOCUS ON SYMPTOMS AND EXCERBATIONS |
| Authors Name: | Rahul Rajendra Mahajan , Nikita Ravindra Morankar |
| Unique Id: | IJSDR2402035 |
| Published In: | Volume 9 Issue 2, February-2024 |
| Abstract: | : Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. While COPD is a mainly chronic disease, a substantial number of patients suffer from exacerbations. Severe exacerbations are related to a significantly worse survival outcome. This review summarises the current knowledge on the different aspects of COPD exacerbations. The impact of risk factors and triggers such as smoking, severe airflow limitation, bronchiectasis, bacterial and viral infections and comorbidities is discussed. More severe exacerbations should be treated with β-agonists and anticholinergics as well as systemic corticosteroids. Antibiotic therapy should only be given to patients with presumed bacterial infection. Noninvasive ventilation is indicated in patients with respiratory failure. Smoking cessation is key to prevent further COPD exacerbations. Other aspects include choice of pharmacotherapy, including bronchodilators, inhaled corticosteroids, phosphodiesterase-4 inhibitors, longterm antibiotics and mucolytics. Better education and self-management as well as increased physical activity are important. Influenza and pneumococcal vaccination is recommended. Treatment of hypoxaemia and hypercapnia reduce the rate of COPD exacerbations, while most interventional bronchoscopic therapies increase exacerbation risk within the first months after the procedure. |
| Keywords: | COPD; Exacerbations;GOLD;Management goals;symptoms. |
| Cite Article: | "GOALS OF COPD TREATEMENT FOCUS ON SYMPTOMS AND EXCERBATIONS", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 2, page no.240 - 250, February-2024, Available :http://www.ijsdr.org/papers/IJSDR2402035.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2402035 Registration ID:210070 Published In: Volume 9 Issue 2, February-2024 DOI (Digital Object Identifier): Page No: 240 - 250 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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