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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15

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Volume 9 | Issue 5

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Paper Title: Microwave assisted, Mont. K10 clay catalyzed solvent-free green synthesis of thiadiazine and quinazolinone derivatives from pyrazole aldehydes and 2-amino amides
Authors Name: M.VETRISELVAN , M.PRAMESH , P.SHANMUGAM , S.JAYANTHI
Unique Id: IJSDR2104089
Published In: Volume 6 Issue 4, April-2021
Abstract: Montmorillonite K10 has been found as a green catalyst for the synthesis of cyclized thiadiazine and quinazolinones derivatives under microwave irradiation and solvent free condition. The scope of the reaction has been demonstrated for a number of pyrazole aldehyde with O-aminoamides such as 2-amino sulfonamide and 2-amino benzamide. The reaction afforded a title compounds within few minutes of irradiation in excellent yield. Synthetic utility of 2-(1,3-diphenyl-1H-pyrazol-4-yl)-6-iodo-2,3-dihydroquinazolin-4(1H)-one has been demonstrated by synthesizing 2-(1,3-diphenyl-1H-pyrazol-4-yl)-6-phenyl-2,3-dihydroquinazolin-4(1H)-one under Suzuki coupling reaction protocol.A plausible mechanism for the formation of product is provided.
Keywords: Microwave irradiation, Montmorillonite K10, pyrazole aldehyde, O-aminoamides, Quinazolinone, thiadiazine.
Cite Article: "Microwave assisted, Mont. K10 clay catalyzed solvent-free green synthesis of thiadiazine and quinazolinone derivatives from pyrazole aldehydes and 2-amino amides", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.6, Issue 4, page no.538 - 545, April-2021, Available :http://www.ijsdr.org/papers/IJSDR2104089.pdf
Downloads: 000337362
Publication Details: Published Paper ID: IJSDR2104089
Registration ID:193176
Published In: Volume 6 Issue 4, April-2021
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.26809
Page No: 538 - 545
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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