A review on Efficasy and Safety of Brexpiprazole for Treatment of Schizophrenia

Andhale Komal Kashinath , Homkar Prajakta Ganesh , Dr.Pawar Pratap Y.

Keywords: brexpiprazole, schizophrenia, Major Depressive Disorder, atypical Antipsychotic.

Abstract: Brexpiprazole has US Food and Drug Administration approval on July 10,2015 monotherapy treatment of schizophrenia and adjunctive treatment to antidepressants for major depressive disorder. It is an Antipsychotic drug.Brexpiprazole is a serotonin-dopamine activity modulator that acts as a partial agonist at serotonin 5-HT1A and dopamine D2 receptors at similar potencies and as an antagonist at5-HT2Aand noradrenaline alpha1B/2Creceptors.These all lead to a favorable antipsychotic profile in terms of improvement of cognitive performance and sleep patterns, as well as effects on affective states and potential to treat core symptoms in Schizophrenia and major depressive disorder, including cognitive deficits with a low risk of adverse effects .Schizophrenia is a serious mental illness that interferes with a person’s ability to think clearly, make decisions ,manage emotions and relate to others. It is a complex, long-term medical illness.

Published Paper   E-Certificate

"A review on Efficasy and Safety of Brexpiprazole for Treatment of Schizophrenia", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.6, Issue 5, page no.109 - 116, May-2021, Available :https://ijsdr.org/papers/IJSDR2105020.pdf

Volume 6 Issue 5, May-2021

Pages : 109 - 116

Paper Reg. ID: IJSDR_193292

Published Paper Id: IJSDR2105020

Downloads: 000347245

Research Area: Pharmacy

Country: Ahmednagar, Maharashtra, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2105020

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2105020

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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