INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Basic rationale of sustained release drug delivery system optimizes the pharmacokinetic, biopharmaceutical, and pharmacodynamics properties of a drug in such a way that its utility is maximized, side-effects are reduced & cure of the disease is achieved. Sustained release dosage forms are designed to release a drug at a predetermined rate by maintaining a constant drug level for a specific period of time with minimum side effects. There are several advantages of sustained release technology over conventional dosage forms like improved patient compliance due to less frequent drug administration, maximum utilisation of the drug, reduction of fluctuation in steady-state drug levels, increased safety margin of potent drug, reduction in healthcare costs through improved therapy and shorter treatment period. Drug release through matrix system is determined by Water penetration, Polymer swelling, Drug dissolution, Drug diffusion, Matrix erosion have been utilized as formulation approaches. The main goal in designing sustained release delivery systems is to reduce frequency of dosing or to increase effectiveness of the drug by localization at the site of the action, reducing dose required or providing uniform drug delivery.
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"A NOVEL APPROACH: SUSTAINED/ CONTROLLED RELEASE DRUG DELIVERY SYSTEM", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 9, page no.341 - 345, September-2022, Available :http://www.ijsdr.org/papers/IJSDR2209053.pdf
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Publication Details:
Published Paper ID: IJSDR2209053
Registration ID:201586
Published In: Volume 7 Issue 9, September-2022
DOI (Digital Object Identifier):
Page No: 341 - 345
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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