INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Diabetes mellitus is hyperglycemic condition that occurs due to defects in insulin secretion or β-cell destruction. Amylin is an 37-amino acid peptide co synthesized and co secreted with insulin which is firstly isolated, purified, and characterized from the amyloid deposits in the pancreases of type 2 diabetics patients. Amylin deficiency occurs in type I and late stage type II diabetes patients due to β-cell destruction. Pramlintide (Symlin®), is an synthetic analogue of the naturally occurring pancreatic hormone amylin, is currently used with insulin in adjunctive therapy for type 1 and type 2 diabetes mellitus. Several synthetic approaches are uesd for synthesis of pramlitide via microwave irradiation. Amylin agonists could also be useful for weight loss, especially in combination with other agents.
"Role of Amylin Analogues in Diabetes mellitus: A Review", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 9, page no.449 - 453, September-2022, Available :http://www.ijsdr.org/papers/IJSDR2209076.pdf
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Publication Details:
Published Paper ID: IJSDR2209076
Registration ID:201655
Published In: Volume 7 Issue 9, September-2022
DOI (Digital Object Identifier):
Page No: 449 - 453
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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