A REVIEW ON MAMMARY GLAND: AS A NON RENAL DRUG EXCRETION ROUTE
Shweta Ramkar
, Sruti Ranjan Mishra
Mammary gland, Milk, Breastfeeding, infant nutrition, Prolactin,
Milk is a mother's diet for her infant, comprising several physiologically active chemicals that play a vital role in newborn and adult nutrition. Nursing is the best type of infant nutrition for the first few months of a newborn's life, and the majority of healthy women start breastfeeding soon after their baby is born. Women on medicine, on the other hand, may resort to formula feeding or refrain from taking their medication for fear of exposing their infant to the medication through breast milk. Although the majority of drugs are thought to be compatible with breastfeeding, there have been reports of substantial baby toxicity, implying that a case-by-case risk assessment should be performed before the mother begins breastfeeding or drug therapy. The introduction of medications used in therapy, as well as environmental contaminants, into milk poses a risk to consumer health. The ability of medicines to transfer into milk is defined by the milk/plasma ratio. The M/P ratios of the medications are influenced by the content of the milk as well as the drug's physicochemical qualities. The drug concentration in milk is determined by drug variables (protein binding, ionisation, molecular weight, lipophilicity, drug-drug and drug-nutrient interactions) and organism (race, species, lactation period, parity, disease and nutrition). However, as our understanding of drug transfer pathways grows, it is becoming clearly obvious that carrier-mediated processes play a role in the excretion of a variety of pharmaceuticals into milk.
"A REVIEW ON MAMMARY GLAND: AS A NON RENAL DRUG EXCRETION ROUTE", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 11, page no.259 - 264, November-2022, Available :https://ijsdr.org/papers/IJSDR2211042.pdf
Volume 7
Issue 11,
November-2022
Pages : 259 - 264
Paper Reg. ID: IJSDR_202488
Published Paper Id: IJSDR2211042
Downloads: 000347246
Research Area: Pharmacy
Country: bastar, chhattisgarh, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
