INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
A REVIEW ON MAMMARY GLAND: AS A NON RENAL DRUG EXCRETION ROUTE
Authors Name:
Shweta Ramkar
, Sruti Ranjan Mishra
Unique Id:
IJSDR2211042
Published In:
Volume 7 Issue 11, November-2022
Abstract:
Milk is a mother's diet for her infant, comprising several physiologically active chemicals that play a vital role in newborn and adult nutrition. Nursing is the best type of infant nutrition for the first few months of a newborn's life, and the majority of healthy women start breastfeeding soon after their baby is born. Women on medicine, on the other hand, may resort to formula feeding or refrain from taking their medication for fear of exposing their infant to the medication through breast milk. Although the majority of drugs are thought to be compatible with breastfeeding, there have been reports of substantial baby toxicity, implying that a case-by-case risk assessment should be performed before the mother begins breastfeeding or drug therapy. The introduction of medications used in therapy, as well as environmental contaminants, into milk poses a risk to consumer health. The ability of medicines to transfer into milk is defined by the milk/plasma ratio. The M/P ratios of the medications are influenced by the content of the milk as well as the drug's physicochemical qualities. The drug concentration in milk is determined by drug variables (protein binding, ionisation, molecular weight, lipophilicity, drug-drug and drug-nutrient interactions) and organism (race, species, lactation period, parity, disease and nutrition). However, as our understanding of drug transfer pathways grows, it is becoming clearly obvious that carrier-mediated processes play a role in the excretion of a variety of pharmaceuticals into milk.
"A REVIEW ON MAMMARY GLAND: AS A NON RENAL DRUG EXCRETION ROUTE", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 11, page no.259 - 264, November-2022, Available :http://www.ijsdr.org/papers/IJSDR2211042.pdf
Downloads:
000336257
Publication Details:
Published Paper ID: IJSDR2211042
Registration ID:202488
Published In: Volume 7 Issue 11, November-2022
DOI (Digital Object Identifier):
Page No: 259 - 264
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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