CLINICAL PROFILING OF CHIKUNGUNYA POSITIVE PATIENTS BY RTPCR IN TERTIARY CARE CENTER,PUNE

Dr.Neha Bagade , Dr.Suvarna Joshi , Dr.Rajesh Karyakarte

Keywords -Chikungunya,Dengue, co-infection, RTPCR,ELISA

Introduction -Chikungunya is a public health problem in Asian,African and Latin American countries.The clinical differentiation of Chikungunya from dengue is very difficult as both diseases share similar clinical signs and symptoms leading to misdiagnosis of Chikungunya in areas where dengue is endemic. Aims and objectives -1)To determine the clinical profiling of IgM ELISA/RTPCR positive patients.2)To determine the distribution of patients diagnosed by RTPCR and ELISA Method-Purposive sampling Result-Out of 1405,320 showed presence of Chikungunya IgM antibodies.Among these 260/320 (81.25%) were Chikungunya positive alone while 60/320(14.6%) showed presence of both dengue and Chikungunya IgM antibodies indicating co-infection.90 patients were having fever <5 days among this 16(17.7%) positive by IgM ELISA and among this 10(62.5%) show PCR positive and 6(37.5%) PCR megative. Discussion -Total 90 patients were tested by RTPCR out of which 55(61.1%) were chikungunya positive.In contrast Philipee Renault et al in their study mentioned 6.17% case detection by RTPCR.In Jean Paul Carrera et al who reported that 44.7% Chikungunya cases detected by RTPCR. Conclusion – The rate of positivity by RTPCR was highest in acute phase first 5 days indicates definitive diagnosis in very early stages.

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"CLINICAL PROFILING OF CHIKUNGUNYA POSITIVE PATIENTS BY RTPCR IN TERTIARY CARE CENTER,PUNE", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 12, page no.847 - 859, December-2022, Available :https://ijsdr.org/papers/IJSDR2212131.pdf

Volume 7 Issue 12, December-2022

Pages : 847 - 859

Paper Reg. ID: IJSDR_203173

Published Paper Id: IJSDR2212131

Downloads: 000347237

Research Area: Medical Science

Country: Amravati , Maharashtra , India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2212131

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2212131

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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