|
INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
Imp Links for Author
Imp Links for Reviewer
Research Area
Subscribe IJSDR
Visitor Counter
Copyright Infringement Claims
Indexing Partner
|
Published Paper Details
|
|
| Paper Title: | Association between renal dysfunction markers and Creatine Kinase levels in Hypothyroidism. |
| Authors Name: | Tejomani M |
| Unique Id: | IJSDR2303038 |
| Published In: | Volume 8 Issue 3, March-2023 |
| Abstract: | Hypothyroidism is one of the most common endocrine disorders in clinical practice. It can affect the kidney function through various mechanisms, such as decreased cardiac output, increased vascular resistance, intrarenal vasoconstriction, reduced production and activity of hormones that regulate blood pressure and fluid balance, and altered kidney structure and feedback. Hypothyroidism can reduce renal plasma flow, glomerular filtration rate, and glomerular transcapillary pressure, which are important for kidney function. Hypothyroid myopathy is a common clinical feature in patients with hypothyroidism. The study was taken up to determine the influence of thyroid hormone on renal dysfunction markers, serum creatinine and cystatin C and on myopathy marker total creatine kinase levels and to evaluate the association between these dysfunction markers in hypothyroid cases. Serum T3, T4, TSH, Total Creatine Kinase, Cystatin C and Creatinine levels were estimated. Creatinine Clearance was calculated by using the Cockcroft-Gault formula and eGFR by using the MDRD formula. The elevation of serum creatinine in the study may be attributed to an increase in total creatine kinase levels which may be due to hypothyroid myopathy or decreased clearance by the kidneys. In contrast to creatinine concentrations, Cystatin C levels are lower in the hypothyroid cases suggesting a paradoxical relationship between them, though both are renal dysfunction markers. Hence interpretation of Cystatin C must be cautiously done in hypothyroidism. |
| Keywords: | Keywords: Creatinine, creatinine clearance, cystatin C, eGFR, hypothyroidism, renal dysfunction, myopathy, thyroid hormone, total creatine kinase. |
| Cite Article: | "Association between renal dysfunction markers and Creatine Kinase levels in Hypothyroidism.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 3, page no.242 - 247, March-2023, Available :http://www.ijsdr.org/papers/IJSDR2303038.pdf |
| Downloads: | 000337217 |
| Publication Details: | Published Paper ID: IJSDR2303038 Registration ID:204174 Published In: Volume 8 Issue 3, March-2023 DOI (Digital Object Identifier): Page No: 242 - 247 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijsdr.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
Track Paper
Important Links
Conference Proposal
ISSN
 |
 |
DOI (A digital object identifier)
  Providing A digital object identifier by DOI How to GET DOI and Hard Copy Related |
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
 |
 |
 |
Social Media
Indexing Partner |
|||
| Copyright © 2024 - All Rights Reserved - IJSDR | |||
Facebook Twitter Instagram LinkedIn