How cancer drugs are discovered and developed

G.M.Mathiazhagan , DR.G.Ariharasivakumar , K.Monica , E.Santhosh kumar , R.Vinoth kumar

Anticancer, Various target statergies, Tubulin, Kinases, Cancer stem cell, Monoclonal antibodies.

Cancer may be a complex malady and its genesis and progression are extraordinarily complex.The largest downside within the malignant neoplasm drug development is deed of multi drug resistance and relapse. Classical chemo therapeutics directly target the polymer of the cell, whereas the modern anticancer medication involve molecular-targeted medical care reminiscent of targeting the proteins possessing abnormal expression within the cancer cells.Standard ways for the complete demolition of the cancer cells tested ineffective.Targeted therapy was successful in bound malignancies however, the effectiveness has usually been restricted by drug resistance and side effects on traditional tissues and cells.Since previous few years, several promising drug targets are known for the effective treatment of cancer. This review article describes a number of these promising malignant neoplasm targets that embrace kinases, tubulin, cancer stem cells, being antibodies and microtuble targeting agents. In addition, promising drug candidates underneath varied phases of clinical trials also are described. Multi-acting medication that simultaneously target completely different neoplastic cell signal pathways might facilitate the method of effective anti-cancer drug development

Published Paper   E-Certificate

"How cancer drugs are discovered and developed", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 3, page no.388 - 395, March-2023, Available :https://ijsdr.org/papers/IJSDR2303060.pdf

Volume 8 Issue 3, March-2023

Pages : 388 - 395

Paper Reg. ID: IJSDR_204404

Published Paper Id: IJSDR2303060

Downloads: 000347192

Research Area: Pharmacy

Country: COIMBATORE, Bannariyamman hostel near, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2303060

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2303060

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition