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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Association Between Microalbuminuria And Severity Of COPD At A Tertiary Care Hospital |
| Authors Name: | Yogesh Kumar Arya , R.K.Panda , Devi Jyoti Dash , Roshan Singh Rathore |
| Unique Id: | IJSDR2304304 |
| Published In: | Volume 8 Issue 4, April-2023 |
| Abstract: | Background & Method: Microalbuminuria (MAB) is a sensitive marker of cardiovascular risk.. MAB is believed to reflect a state of generalized endothelial dysfunction, and therefore it is an emerging therapeutic target for primary prevention strategies.Microalbuminuria can be present in COPD patients due to hypoxemia.The aim of the study was to know association between microalbuminuria and severity of COPD at a tertiary care hospital. Patients with COPD who had fulfilled inclusion and exclusion criteria were included in study. They were divided into four GOLD different groups, namely A,B,C and D based on the COPD assessment (CAT) score and number of exacerbations. A CAT score of more than 10 was denoted a patient as having more symptoms and a history of exacerbations of 2 or more than 2 in a year was` denoted as patient having more risk of COPD and urine albumin creatinine ratio was taken . Result: Among 138 microalbuminuria cases 42% were among mmrc grade-4, 26.1% were in mmrc grade-3, 27.5% were among mmrc grade-2 and 4.3% were in mmrc grade 1. In 10 cases with absent microalbuminuria 70% were in grade-2. Association was tested using chi square test and it statistically significant (p=0.002). Among 138 microalbuminuria cases 40.5% had GOLD group -D,8.1% had GOLD group c,21.6% had group GOLD B,and 29.7% had GOLD group A and all of the cases in 10 cases with absent microalbuminuria had GOLD group A. Association was tested using chi square test and it statistically significant (p<0.001). Conclusion: The results of this study specify a solid association between microalbuminuria and increasing severity in COPD patients. Therefore, COPD patients should undergo routine microalbuminuria screening because it increases the risk of endothelial injury, which plays a major role in the pathogenesis of Cor Pulmonale. The determination of microalbuminuria is simple and inexpensive. |
| Keywords: | : microalbuminuria, severity, COPD & tertiary |
| Cite Article: | "Association Between Microalbuminuria And Severity Of COPD At A Tertiary Care Hospital", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.1967 - 1971, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304304.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2304304 Registration ID:205576 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: 1967 - 1971 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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