INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
EMERGING HELICOBACTER PYLORI RESISTANCE AND ITS ERADICATION
Authors Name:
GURUPRAKASH RAJA
, Manivasakam P
Unique Id:
IJSDR2306001
Published In:
Volume 8 Issue 6, June-2023
Abstract:
Helicobacter pylori is a gram-negative bacterium that infects roughly 4.4 billion people globally. Its prevalence varies geographically and is affected by a variety of factors. Various national and international guidelines for the management of H. pylori have been regularly updated for eradication. Recent worldwide guidelines for treating H. Pylori infections recommend bismuth or non-bismuth triple therapy for 14 days as a first-line treatment for H. Pylori in areas of high clarithromycin and/or metronidazole resistance. Antibiotic resistance in H. pylori has drastically increased on a global scale, which has an impact on the effectiveness of treatment. Although effective antibiotic therapy must be based on susceptibility testing, increasing antimicrobial resistance and widespread lack of antimicrobial susceptibility have led physicians to mostly depend on empiric regimens. Triple therapy with clarithromycin is no longer the recommended treatment for H. Pylori owing to the rising prevalence of antibiotic resistance, especially in some areas where local resistance to this treatment is over 20%. Alternative methods of eradicating H. Pylori infection have been proposed. Some of the novel therapeutic agents include vonoprazon, Levofloxacin and probiotic supplements. Although these new therapeutic interventions offer respectable H. Pylori eradication rates, they should not make H. Pylori more resistant to antimicrobials in the future.
Keywords:
H. Pylori; Resistance; Eradication; Treatment
Cite Article:
"EMERGING HELICOBACTER PYLORI RESISTANCE AND ITS ERADICATION", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 6, page no.1 - 7, June-2023, Available :http://www.ijsdr.org/papers/IJSDR2306001.pdf
Downloads:
000337351
Publication Details:
Published Paper ID: IJSDR2306001
Registration ID:202799
Published In: Volume 8 Issue 6, June-2023
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.36206
Page No: 1 - 7
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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