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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | UPLC: A Review |
| Authors Name: | Yogesh Uttamrao Dhumale , S. S. Bhokare , M. S. Charde , R. D. Chakole , S.R. Chormale |
| Unique Id: | IJSDR2306142 |
| Published In: | Volume 8 Issue 6, June-2023 |
| Abstract: | Chromatography is a non-destructive method that uses a porous material and solvents to separate a mixture of components into their individual components. UPLC is a modern analytical technique. UPLC refers to ultra-performance liquid chromatography. This technique improves three areas of liquid chromatography: Speed, resolution, and sensitivity. In this system, columns contain fine particle sizes (less than 1.7 m). Due to the small partical size, it decreases the length of the column, saves time, and reduces solvent consumption. The design of this system is such that it can withstand high system backpressures. In the twenty-first century, pharmaceutical industries and analytical laboratories mainly focused on reducing time and also decreasing cost in new drug development The Van Deemter relationship, which explains the link between flow rate and plate height (HETP), is the foundation of the UPLC method. This review shows the theories which are used in separation technology related with UPLC and also tells about its applications. |
| Keywords: | UPLC, HPLC, Separation, Quantification, Resolution, Sensitivity, |
| Cite Article: | "UPLC: A Review", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 6, page no.994 - 1000, June-2023, Available :http://www.ijsdr.org/papers/IJSDR2306142.pdf |
| Downloads: | 000337351 |
| Publication Details: | Published Paper ID: IJSDR2306142 Registration ID:207241 Published In: Volume 8 Issue 6, June-2023 DOI (Digital Object Identifier): Page No: 994 - 1000 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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