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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Development and Evaluation of Floating Tablet of Metformin Hydrochloride Using Different Polymers |
| Authors Name: | Manchuke Asha Vitthal , Pooja R. Gawandar , Dr. Kailash R. Biyani. |
| Unique Id: | IJSDR2306161 |
| Published In: | Volume 8 Issue 6, June-2023 |
| Abstract: | Abstract: In terms of delivering the medication to the stomach for an extended period of time, the creationof a gastro-retentive dosage form for Metformin employing Xanthan gum and carbopol has shown encouraging results. The optimized formulation (F5) demonstrated the optimum drug release profile, suggesting that employing Xanthan gum and carbopol in floating tablets can be a workable strategy for obtaining the intended outcomes of gastro-retentive floating tablets. The formulation of floating tablets with various polymers can also affect how effective and bioavailable they are.This study demonstrates the potential of floating tablets as a drug delivery system, which can provide various benefits over traditional tablets, including enhanced bioavailability and therapeutic efficacy, decreased dose frequency, and improved patient compliance. Additional research can be done to assess the formulation's safety and effectiveness in living organisms and to determine the ideal concentration of Xanthan gum and carbopol for use in additional medications with comparable pharmacokinetic profiles. |
| Keywords: | Keywords: Metformin Hydrochloride, Floating Tablets, Xanthan gum Carbopol |
| Cite Article: | "Development and Evaluation of Floating Tablet of Metformin Hydrochloride Using Different Polymers", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 6, page no.1145 - 1155, June-2023, Available :http://www.ijsdr.org/papers/IJSDR2306161.pdf |
| Downloads: | 000337350 |
| Publication Details: | Published Paper ID: IJSDR2306161 Registration ID:207328 Published In: Volume 8 Issue 6, June-2023 DOI (Digital Object Identifier): Page No: 1145 - 1155 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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