A Multi-centre study: Chest radiographic findings in adult patients with HIV/PTB co-infection and their CD4+ count
Nwosu, Chinekwu Skye
, Uzukwu, Ifeanyi Olisa , Eze, Kenneth .C. , Azubiuke, Chinedu .G. , Obi-Nwosu, Amaka Lovelyn
CD4+ count, HIV/PTB co-infection, tuberculosis
A MULTI-CENTRE STUDY: CHEST RADIOGRAPHIC FINDINGS IN ADULT PATIENTS WITH HIV/PTB CO-INFECTION AND THEIR CD4 COUNT. Uzukwu IO, Nwosu, CS, Eze KC, Azubuike CG, Emegoakor AC, Okorie AP, Obi-Nwosu AL, Uke KC ABSTRACT INTRODUCTION Tuberculosis (PTB) is a major global health problem, one-fourth of the world’s population is infected with the disease. The radiographic findings are atypical in the immuno-compromised and it resembles the primary type. AIM To determine the relationship between Chest radiographic findings of patients diagnosed with HIV/PTB co-infection and their CD4+ count. METHODS A cross-sectional, descriptive plain chest radiographic evaluation of pulmonary tuberculosis in patients with HIV/AIDS and their CD4+ count levels. RESULTS Nineteen subjects with HIV/PTB co-infection showed normal chest X-ray findings (CXR) . More females with CD4+ count < 200/mms3 (44 versus 33 for male to female values) while CD4+ count of > 200/mm3 showed more males (20 versus 15 for male to female values). Lobar pneumonia, miliary, cystic changes, fibrosis, and effusion were seen more in HIV/PTB subjects with CD4+ count < 200/mm3 with p- values of < 0.001, 0.016, 0.10, 0.003, and 0.016 respectively. Atypical CXR findings were seen in more subjects with a CD4+ count of <200mm3 (35) versus a CD4+ count of > 200mm3 (2) with a p-value of 0.001. The typical CXR findings were seen more in subjects with CD4+ counts of > 200/mm3 (27) versus those with CD4+ counts of < 200mm3 (9). CONCLUSION Patients with HIV/PTB co-infection have a significant chance of manifesting atypical CXR findings than typical CXR findings. KEYWORDS: CXR findings, CD4+ count, HIV/PTB co-infection, male-to-female values, radiographic.
"A Multi-centre study: Chest radiographic findings in adult patients with HIV/PTB co-infection and their CD4+ count", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 7, page no.178 - 187, July-2023, Available :https://ijsdr.org/papers/IJSDR2307025.pdf
Volume 8
Issue 7,
July-2023
Pages : 178 - 187
Paper Reg. ID: IJSDR_207594
Published Paper Id: IJSDR2307025
Downloads: 000347205
Research Area: Medical Science
Country: Awka, Anambra, Nigeria
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
