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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Method development, validation and rapid determination of Cetirizine Hydrochloride drug by chromatographic technique. |
| Authors Name: | Anil Nishad , Dr. Gayatri Barabde , Dr. Sushma Ambadekar , Dr. Amit Padelkar |
| Unique Id: | IJSDR2307094 |
| Published In: | Volume 8 Issue 7, July-2023 |
| Abstract: | A simple, sensitive, precise and accurate reverse phase liquid chromatographic method for the analysis of Cetirizine hydrochloride has been developed and validated. This method is used for the determination of compounds in commercial pharmaceutical products. The compounds were well separated on a C18 column [ Inertsil C18, 5µm, 150 x 4.6 mm] utilizing a mobile phase consisting of acetonitrile: phosphate buffer (45:55 (v/v), pH7.0) at a flow rate of 1.0 ml/min with UV detection at 230 nm. The retention time of Cetirizine hydrochloride was found to be 3.11minute.With this method linearity was observed (Correlation coefficient=0.999). According to the validation results, the proposed method was found to be specific, accurate, precise and rapid. Hence the same can be applied to the quantitative analysis of tablets containing Cetirizine hydrochloride. |
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| Cite Article: | "Method development, validation and rapid determination of Cetirizine Hydrochloride drug by chromatographic technique.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 7, page no.642 - 648, July-2023, Available :http://www.ijsdr.org/papers/IJSDR2307094.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2307094 Registration ID:207760 Published In: Volume 8 Issue 7, July-2023 DOI (Digital Object Identifier): Page No: 642 - 648 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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