INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
The increasing use of recombinantly expressed therapeutic proteins in the pharmaceutical industry has highlighted issues such as their stability during long-term storage and means of efficacious delivery that avoid adverse immunogenic side effects. Controlled chemical modifications, such as substitutions, acylation and PEGylation, have fulfilled some but not all of their promises, while hydrogels and lipid-based formulations could well be developed into generic delivery systems. Strategies to curb the aggregation and misfolding of proteins during storage are likely to benefit from the recent surge of interest in protein fibrillation. This might in turn lead to generally accepted guidelines and tests to avoid unforeseen adverse effects in drug delivery. Drugs are substances that change a person's mental or physical state. They can affect the way your brain works, how you feel and behave, your understanding and your senses. This makes them unpredictable and dangerous, especially for young people. The effects of drugs are different for each person and drug. Drug education helps children and young people understand that all drugs, legal and illegal, have the potential to cause harm, and that the drug experience is because of many factors including the person, the drug and the environment.
Keywords:
drug stability, protein fibrillation, drug delivery system
Cite Article:
"DRUG STABILITY", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 8, page no.941 - 948, August-2023, Available :http://www.ijsdr.org/papers/IJSDR2308138.pdf
Downloads:
000338719
Publication Details:
Published Paper ID: IJSDR2308138
Registration ID:208253
Published In: Volume 8 Issue 8, August-2023
DOI (Digital Object Identifier):
Page No: 941 - 948
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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