Pharmacological Investigations of Ethanolic Roots Extract of Asparagus racemosus Willd

Pratibha Singh , Amrita Singh , Muskan Saxena , Bhanu P. S. Sagar

Anti-inflammatory, carageenan, flavonoids, herbal medicines, indomethacin, natural products. paw edema, physicochemical, shatavari, solvent extractive values

Identity and purity of shatavari roots were established pharmacognostically and herbarium specimen IEC/Pharm/Herb/2022/2224 was deposited in Herbarium Bank. Shatavari roots confirmed phenolic compounds, alkaloids, sterols, flavanoids, steroidal glycosides isoflavones, and tannins. In physicochemical analysis of roots of Asparagus racemosus, roots were free from contamination (low ash values), AIAV 1.6 % (Low acid-insoluble ash values) indicated drug was free from siliceous matters / sand, WSAV 4.42 % (Water soluble ash value) indicated presence of water soluble salts and ASEV (7.94 %), WSEV (8.62%) (solvent extractive values) indicated presence of phyto-constituents and 2.68% (LOD). Asparagus racemosus Willd. EERAR extract induced powerful Rat RBC membrane stabilizing property (45.24% to 86.56% membrane stabilization impact of EERAR). Asparagus racemosus Willd. (shatavari) EERAR (A/B) produced impactful anti-inflammatory activity. The indomethacin induced excellent anti-inflammatory (edema reduced significantly). Asparagus racemosus Willd. EERAR roots extract contains phenolics, sterols and flavonoids possess significant inflammatory effects. Indomethacin and EERAR-B anti-inflammatory effects were very good in comparison of drug vehicle control group (significant at P<0.05 over control). Further, in Cotton pellet-induced granuloma method, Indomethacin (10 mg/kg) inhibition 53.20% ; EERAR-B: (400 mg/kg) inhibition 32.82%; values were significant at p < 0.05).

Published Paper   E-Certificate

"Pharmacological Investigations of Ethanolic Roots Extract of Asparagus racemosus Willd", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 9, page no.785 - 805, September-2023, Available :https://ijsdr.org/papers/IJSDR2309120.pdf

Volume 8 Issue 9, September-2023

Pages : 785 - 805

Paper Reg. ID: IJSDR_208662

Published Paper Id: IJSDR2309120

Downloads: 000347260

Research Area: Engineering

Country: -, -, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2309120

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2309120

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition