Comparative Pharmacological Assessment of Polyherbal Formulation Immunoboost Tablet and Immunoboost Herbal Extract Capsule

Renu Kaushik , Amrita Singh , Mohd Zafar , Bhanu P. S. Sagar

Antioxidant, anti-inflammatory, Immunomodulators, Immunosuppressants, Immunoadjuvants, total phenolic content, total flavonoid content.

In current scenario, more than 500 Immunomodulatory phytoformulations are globally commercial available either online or offline for prophylactic use (food supplements) therapeutic use (immunomodulatory) to strengthen the body immunity. At yet, Immuno Boost Tablet (IBT, NatureFlip) and Immuno Boost Herbal Extract Capsule (IBHEC, Medinutrica) are not scientifically pharmacologically assessed for their immunomodulatory and other pharmacological investigations. So, present investigation was an attempt to investigate pharmacological potential of IBT and IBHEC. IBT showed 94 SPMs in dried aqueous extract / powder of 12 plants (Haritaki, Amla, Baheda, Haldi, Kali Mirch, Pippali, Guduchi, Yastimadhu / Mulethi, Tulsi, Chitrak, Sounth and Manjishta) whereas IBHEC indicated 44 SPMs in dried aqueous extract of 05 medicinal plants (Amla, Tulsi, Giloy, Haldi and Mulethi). On comparison, IBT was found to be more powerful immunomodulatory then IBHEC. Besides, both IBT and IBHEC were found to be non-toxic / non-lethal (no mortality found even at dose of 2000 mg/kg) with wide safety margin (free from side effects / lethal toxicity). Further, both formulations indicated presence of PPMs and SPMs of all categories and due to high phenolic and flavonoid content in IBT it showed high TPC and TFC content and better antioxidant properties then IBHEC. Both IBT and IBHEC showed good adaptogenic properties and also produced significant anti-inflammatory effects (decrease in edema) when compared with Indomethacin (standard drug).

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"Comparative Pharmacological Assessment of Polyherbal Formulation Immunoboost Tablet and Immunoboost Herbal Extract Capsule", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 9, page no.806 - 828, September-2023, Available :https://ijsdr.org/papers/IJSDR2309121.pdf

Volume 8 Issue 9, September-2023

Pages : 806 - 828

Paper Reg. ID: IJSDR_208663

Published Paper Id: IJSDR2309121

Downloads: 000347285

Research Area: Pharmacy

Country: -, -, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2309121

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2309121

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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