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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Study of comparison of various quality control test for expired and non-expired medicine |
| Authors Name: | Tamboli Asiya Yusuf , Waghmare Samruddhi Kishor , Prof. Sole Patil P.P , Dr. Kolhe S.D |
| Unique Id: | IJSDR2309125 |
| Published In: | Volume 8 Issue 9, September-2023 |
| Abstract: | Paracetamol is an antipyretic medicine that belongs to the non-steroidal anti-inflammatory drug class. There are some dosage forms on the market under different names that all have the general claim to be bioequivalent. The main purpose of this experiment is to determine the difference between expired and non-expired medicine. To our knowledge, very few of these studies have been conducted on expired drugs. In addition, most of these studies are related to the stable physical and chemical properties of expired drugs, and no studies have been conducted to confirm their efficacy. In this study, Paracetamol 650 mg standard tablets from different companies were selected. Compression parameters (such as weight change, brittleness, hardness, and dissolution profile) may be found in many ways. Evaluation of these limits is done before maturity, after maturity, and every six months for two years from the expiration date to form a basis. At the time of the research, the active ingredients of all drugs were guaranteed intellectual property, indicating that they retained their potency two years after expiration. Antibiotics, determined by the patterns of "radiant heat tail movement" and "acetic acid-induced writhing", were not significantly different in efficacy and per cent protection. This shows that the drug maintains its results. Small difference in time of explosion during expiration compared to the time difference. |
| Keywords: | Key words: Paracetamol, friability test, weight variation test, hardness test, disintegration test, dissolution test. |
| Cite Article: | "Study of comparison of various quality control test for expired and non-expired medicine", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 9, page no.876 - 880, September-2023, Available :http://www.ijsdr.org/papers/IJSDR2309125.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2309125 Registration ID:208685 Published In: Volume 8 Issue 9, September-2023 DOI (Digital Object Identifier): Page No: 876 - 880 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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