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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Hematological parameters in diabetic patients-an institutional study |
| Authors Name: | Dr. Swathy Shanker , Dr.Afeefa Ammengara |
| Unique Id: | IJSDR2310017 |
| Published In: | Volume 8 Issue 10, October-2023 |
| Abstract: | Type 2 Diabetes mellitus is a metabolic disease characterized by impaired glucose tolerance and insulin resistance. WHO has predicted that the prevalence of DM worldwide will be 592 million by the year 2035. The hematological changes in Diabetes Mellitus are linked to inflammation and endothelial dysfunction. Alteration in size, morphology and functions of RBCs, WBCs and platelets are assumed to be responsible for the metabolic effects of hyperglycemia. Previous studies have implicated a rise in WBC count as a prognostic factor for development of cardiovascular complications in DM. Elevated MPV, PDW, Platelet count and RDW in patients with poor glycemic control has been shown to be predictors of endothelial dysfunction. Aim-This study aims to find the variation in CBC indices and compare it to a non-diabetic population to evaluate its statistical significance. Method- A cross –sectional study was carried out among patients who were known cases of diabetes mellitus, attending a tertiary care hospital during the month of January 2023. Total of 276 subjects were included in this study, with 138 diabetic patients and 138 non-diabetic subjects. Result- The current study shows that there is significant decrease in RBC values while RDW-SD is elevated in diabetic patients. Total WBC count, ANC and NLR are drastically increased in th diabetic population. Conclusion- In concordance with previous studies, it shows the need for monitoring these values for predicting the outcome or occurrence of micro and macro vascular complications. |
| Keywords: | Type 2 Diabetes Mellitus, Complete Blood Count, vascular complications |
| Cite Article: | "Hematological parameters in diabetic patients-an institutional study", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 10, page no.95 - 101, October-2023, Available :http://www.ijsdr.org/papers/IJSDR2310017.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2310017 Registration ID:208816 Published In: Volume 8 Issue 10, October-2023 DOI (Digital Object Identifier): Page No: 95 - 101 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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