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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Peripheral smear and CBC findings in CAD patients:a cross-sectional study |
| Authors Name: | Dr. Swathy Shanker , Dr. Afeefa Ammengara |
| Unique Id: | IJSDR2310053 |
| Published In: | Volume 8 Issue 10, October-2023 |
| Abstract: | Cardiovascular diseases (CVD) are common non communicable disease and have high mortality rate globally, accounting for around 60% of all deaths. Recent studies have proved the association of various hematological parameters with cardiovascular diseases, including Red Cell Distribution Width(RDW), Mean Platelet Volume(MPV) and Neutrophil-Lymphocyte Ratio (NLR). Aim- In this study, we aim to find the alterations in RBC morphology and other Complete Blood Count (CBC) parameters in patients with Coronary Artery Diseases (CAD) by comparing the values and peripheral smear findings with that of normal population. Method- Peripheral smears and CBCs of 44 females and 56 males were reviewed from both normal population and patients with CAD, making a total of 200 cases. Blood samples were processed and evaluated by Auriba ABX Penta xlr hematology analyser. Data analysis: Data was entered and tabulated in Microsoft Excel and analyisis was carried out by SPSS software (version 16.0). Result- Among the RBC parameters compared, Mean Corpuscular Volume (MCV) showed no significant change in CAD population as compared to normal population. Other parameters showed significant difference .Among the platelet parameters reviewed, Platelet Distribution Width (PDW) showed a significant increase in CAD patients when compared to normal population. Other parameters showed insignificant change. Conclusion- According to this study, the RBC parameters have been significantly reduced in patients with CAD whereas RDW has been found to be significantly increased indicating increased anisopoikilocytosis. Higher WBC count and NLR has also been documented similar to other studies, while platelet parameters except PDW showed statistically insignificant changes. |
| Keywords: | Cardiovascular diseases, Complete blood Count, Peripheral smear |
| Cite Article: | "Peripheral smear and CBC findings in CAD patients:a cross-sectional study", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 10, page no.307 - 312, October-2023, Available :http://www.ijsdr.org/papers/IJSDR2310053.pdf |
| Downloads: | 000338721 |
| Publication Details: | Published Paper ID: IJSDR2310053 Registration ID:208893 Published In: Volume 8 Issue 10, October-2023 DOI (Digital Object Identifier): Page No: 307 - 312 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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