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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Comparative Pharmacological Assessment of Indian Polyherbal Formulations Amlycure DS Syrup and Yakriamrit Syrup |
| Authors Name: | Pooja Khatri , Amrita Singh , Snehil Singh , Mohd Zafar , Bhanu P. S. Sagar |
| Unique Id: | IJSDR2311031 |
| Published In: | Volume 8 Issue 11, November-2023 |
| Abstract: | On the basis of composition, Amlycure DS syrup contains better and more scientific anti-hepatotoxic herbals drugs (pharmacological investigations of individual herbal drugs have been established scientifically) than Yakriamrit Syrup. Amlycure DS and Yakriamrit Syrup both produced superoxide radical scavenging activity. The findings indicated that Amlycure DS and Yakriamrit Syrup both were hepatoprotective. It has been concluded that hepatoprotective activity of the Amlycure DS and Yakriamrit Syrup (Phenolic and tannins of the formulation contribute to scavenging and inhibition of lipid oxidation). Amlycure DS and Yakriamrit Syrup (herbal Syrup formulation showed reversal effects which was clearly indicated by reddish coloration, normal anatomical architecture of the hepatocytes. Amlycure DS formulations showed a remarkable anti- hepatotoxic activity but comparatively lesser anti-hepatotoxic effects then standard reference drug i.e. Silymarin. It has been concluded that Amlycure DS and Yakriamrit Syrup herbal Syrup formulation produced therapeutic effects like attenuation of depletion of glutathione; membrane stabilization (stop necrosis); increased proteins synthesis (RNA repair); Anti-oxidant (stops lipid per-oxidation) activity. |
| Keywords: | Anti-hepatotoxic, Amlycure DS Syrup, Drug-induced Liver injury, hepatocytes, paracetamol, secondary plant metabolites (SPM), total phenolic content (TPC), total flavonoid content (TFC), Silymarin, Yakriamrit Syrup, Phenolics, Tannins |
| Cite Article: | "Comparative Pharmacological Assessment of Indian Polyherbal Formulations Amlycure DS Syrup and Yakriamrit Syrup", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 11, page no.208 - 221, November-2023, Available :http://www.ijsdr.org/papers/IJSDR2311031.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2311031 Registration ID:209253 Published In: Volume 8 Issue 11, November-2023 DOI (Digital Object Identifier): Page No: 208 - 221 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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