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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Treatment of Old World cutaneous leishmaniasis with oral dapsone and radiofrequency machine alone and in combination in Aljabal Algharby Libya |
| Authors Name: | Ahlam AB ALMABROUK , Ali O DAEKI |
| Unique Id: | IJSDR2311052 |
| Published In: | Volume 8 Issue 11, November-2023 |
| Abstract: | Background: Cutaneous leishmaniasis (CL) is a disease transmitted by infected sandflies in tropical and subtropical areas of the world. Over 12 million people are infected with CL, with 90% of cases occurring in Afghanistan, Iran, Algeria, Brazil, Peru, Saudi Arabia, Syria, and Libya. CL causes localized skin lesions that may disappear without treatment or persist, causing severe tissue damage, permanent disfigurement, and serious disability. Physical methods such as cryotherapy, heat therapy, photodynamic therapy, laser, and radiofrequency have shown promising results in treating CL. However, none of the suggested treatments are universally effective, and many of them are associated with serious local and systemic side effects. Early diagnosis and treatment can cure the disease, prevent psychological impact, and help in the prevention of transmission. Different therapeutic modalities (monotherapy or combined therapy) were used in patient treatment, with different approaches planned according to the severity and duration of the condition. Patients and Methods: The study was conducted on 60 Patients who were divided into three groups: 20 patients treated with dapsone tab 100mg once daily for one month and 20 with radiofrequency, the third group, 20 Patients were treated with a combination of dapsone tab 100mg and radiofrequency. Treatment sessions were scheduled for 1 session every 2 weeks. Statistical analysis was carried out using SPSS software version 18 (USA). Results and Discussion: Patients underwent weekly physical exams to evaluate the clinical response and adverse effects. Clinical response was classified as complete, good, or poor. Data were analyzed using one-way NOVA, Turkey's test, chi-square test, ANOVA, and Fischer's exact test. There was no significant difference among the studied groups regarding demographic data. Patients treated with dapsone and radiofrequency were significantly more cleared in 1-2 months than those treated with radiofrequency alone. Conclusion: Patients had weekly physical exams to evaluate the clinical response and adverse effects. Clinical response was classified as complete, good, or poor. Data was analyzed using various tests. Dapsone and radiofrequency-treated patients cleared more in 1-2 months. |
| Keywords: | Cutaneous leishmaniasis, dapsone, radiofrequency, algabal Algarby, Libya. |
| Cite Article: | "Treatment of Old World cutaneous leishmaniasis with oral dapsone and radiofrequency machine alone and in combination in Aljabal Algharby Libya", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 11, page no.362 - 366, November-2023, Available :http://www.ijsdr.org/papers/IJSDR2311052.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2311052 Registration ID:209235 Published In: Volume 8 Issue 11, November-2023 DOI (Digital Object Identifier): https://doi.org/10.5281/zenodo.10156276 Page No: 362 - 366 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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