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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Preparation and Evaluation of Transdermal patch using three Ficus bark Extracts |
| Authors Name: | Vishwamyna S , Bhuvaneshwari J , K.B. Neha |
| Unique Id: | IJSDR2311109 |
| Published In: | Volume 8 Issue 11, November-2023 |
| Abstract: | Transdermal drug delivery system is an adhesive patch applied to the skin that contains medication that is intended to be absorbed into the bloodstream through the skin. It has advantages over conventional dosage forms like reduce side effect, control and steady delivery, easy application, reduces the frequency of administration. In the study an attempt was made to prepare a transdermal patch using the bioactive extracts of three Ficus species- F. Benghalensis, F racemosa and F religiosa. These plants are known to have chemical constituents which have wound healing, antimicrobial and antioxidant activity. A patch with these extracts can help overcome the side effects of synthetic medicines. Extracts showed presence of phenols, carbohydrates flavonoids, anthraquinones and saponins. The individual extracts were standardised by estimation of total phenol and flavonoid content. The combined aqueous and methanolic extracts combination contained 1.12% and 1.129% total Polyphenol content and 0.55% and 0.64% flavonoid content respectively. Using Combination of three water extracts and three methanolic extracts, patch was prepared and evaluated for physico- chemical parameters. The physico- chemical parameters of prepared transdermal patch were satisfactory. The patch prepared with methanolic extracts of the barks showed polyphenol and flavonoid content. Hence the extracts can be successfully formulated as transdermal patch. |
| Keywords: | Ficus benghalensis Linn., Ficus religiosa Linn, Ficus racemosa Roxb, transdermal patch, |
| Cite Article: | "Preparation and Evaluation of Transdermal patch using three Ficus bark Extracts", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 11, page no.710 - 724, November-2023, Available :http://www.ijsdr.org/papers/IJSDR2311109.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2311109 Registration ID:209428 Published In: Volume 8 Issue 11, November-2023 DOI (Digital Object Identifier): Page No: 710 - 724 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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