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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Pharmacological and Toxicological Evaluation of Divya Swasari Coronil Kit |
| Authors Name: | Priyanka Maity , Dr. Bhanu P. S. Sagar , Dr. Amrita Singh , Snehil Singh , Mohd Zafar |
| Unique Id: | IJSDR2312024 |
| Published In: | Volume 8 Issue 12, December-2023 |
| Abstract: | In the present investigation an attempt has been made to assess the pharmacological potential of Divya-Coronil-Kit comprising of Coronil tablet, Swasari Vati and Anu Taila for management and control of Covid-19 infections. On evaluation, it was found that DCK containing Coronil Tablet, Swasari Vati and Anu Taila. Coronil Tablet contains 25 SPMs from 03 Medicinal Plants. Divya Swasari Ras Vati contains 89 SPMs from 09 Drugs whereas Anu Taila contains 204 phytoconstituents / SPMs from 27 Herbal Drugs. Coronil Tablet acts as immunity Booster. Divya Swasari Ras Vati is useful in cold, cough, and other viral diseases). Divya Anu Taila act internally for cooling brain and nerves; Improves sensory organs functions). Coronil Tablet, Swasari Vati and Anu Taila indicated the presence of alkaloids, glycosides, resins, terpenes, flavonoids, phytosterols, tannins, saponins, reducing sugars, anthraquinones, steroids, proteins, amino-acids. High amount of total phenolic content (TPC) and total flavonoid content (TFC) were found in the Coronil Tablet and Swasari Vati. A high amount of TFC was found in the Coronil Tablet but less than Divya Swasari Ras Vati. Coronil Tablet extract has also induced significant NO scavenging activity and antioxidant activity of Coronil Tablet was significant. Acute Toxicity studies clearly indicated that there was no mortality in rats upto 2000 mg/kg/b.wt. Coronil tablet and Swasari Vati induced a very wide safety margin and classified as Non-Toxic. Both Coronil Tablet and Swasari Vati increased swimming endurance and produced significant decrease in edema (significant anti-inflammatory effects) but effects were comparatively less significant than standard reference drug i.e. Indomethacin. |
| Keywords: | Adaptogenic, anti-inflammatory, antioxidant, acute toxicity, Coronil tablet, sub-acute toxicity, Swasari Ras Vati, swimming test, free radical scavenging activity, total phenolic content, total flavonoid content |
| Cite Article: | "Pharmacological and Toxicological Evaluation of Divya Swasari Coronil Kit", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 12, page no.176 - 191, December-2023, Available :http://www.ijsdr.org/papers/IJSDR2312024.pdf |
| Downloads: | 000338720 |
| Publication Details: | Published Paper ID: IJSDR2312024 Registration ID:209498 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: 176 - 191 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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