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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | OCCULAR DRUG DELIVERY SYSTEM : NOVEL TECHNIQUES OF HYDROGELS TARGETING SYSTEM ON POSTERIOR SEGMENT DISEASE |
| Authors Name: | MAYURI SAINATH AVDHUT , DISHA DILIP ADE , SNEHAL SUDHAKAR DHEWALE , DIPALI DAMODHAR BALERAO , DIPAK UTTAM ADHAV |
| Unique Id: | IJSDR2312066 |
| Published In: | Volume 8 Issue 12, December-2023 |
| Abstract: | Ocular drug delivery has been a major challenge due to the unique anatomy and physiology of the eye. Treatment for Posterior segment disease still remains a huge task for formulation scientist. Ocular drug delivery using injectable hydrogel involves the administration of therapeutic agents directly into the eye in the form of gel. Ocular drug delivery has been a major challenge due to the unique anatomy and Hydrogels are generally a series of relatively hydrophilic polymers with the ability to form three dimensional across linked network and preserve large amount of water. Hydrogels are multifunctional ophthalmic drug delivery systems capable of extending drug residence time and sustaining release of drugs. An injectable hydrogel is generally based on the idea that some biomaterials can be injected as liquid into human body. Thermogels, or thermo-responsive hydrogels, are a subclass of the supramolecular hydrogels that gelate via hydrophobic interactions. Thermogels are temperature-sensitive hydrogels that can transition from a liquid to a gel state. In ocular drug delivery, thermogels are used to improve drug retention and sustained release on the ocular surface. In this review, injectable hydrogel, posterior segment diseases and corresponding Treatments are briefly introduced. In addition of temperature responsive hydrogel also described in brief. |
| Keywords: | ODDS, Ocular drug delivery, Injectable hydrogel, Posterior segment, Thermogel. |
| Cite Article: | "OCCULAR DRUG DELIVERY SYSTEM : NOVEL TECHNIQUES OF HYDROGELS TARGETING SYSTEM ON POSTERIOR SEGMENT DISEASE", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 12, page no.488 - 498, December-2023, Available :http://www.ijsdr.org/papers/IJSDR2312066.pdf |
| Downloads: | 000338719 |
| Publication Details: | Published Paper ID: IJSDR2312066 Registration ID:209572 Published In: Volume 8 Issue 12, December-2023 DOI (Digital Object Identifier): Page No: 488 - 498 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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